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BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition
scientific article
BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
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scholarly article
1 reference
stated in
PubMed
PubMed ID
24345920
retrieved
13 November 2016
title
BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition
(English)
1 reference
stated in
PubMed
PubMed ID
24345920
retrieved
13 November 2016
author
William Pao
series ordinal
13
0 references
Igor Puzanov
series ordinal
11
0 references
Jennifer A. Pietenpol
series ordinal
9
object named as
Jennifer A Pietenpol
0 references
Brian D. Lehmann
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author name string
Katherine E Hutchinson
series ordinal
1
0 references
Doron Lipson
series ordinal
2
0 references
Philip J Stephens
series ordinal
3
0 references
Geoff Otto
series ordinal
4
0 references
Brian D Lehmann
series ordinal
5
0 references
Pamela L Lyle
series ordinal
6
0 references
Cindy L Vnencak-Jones
series ordinal
7
0 references
Jeffrey S Ross
series ordinal
8
0 references
Jeffrey A Sosman
series ordinal
10
0 references
Vincent A Miller
series ordinal
12
0 references
language of work or name
English
0 references
publication date
15 December 2013
0 references
published in
Clinical Cancer Research
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volume
19
0 references
page(s)
6696-702
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issue
24
0 references
cites work
BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors
1 reference
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PubMed Central
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20 March 2017
Trim24 targets endogenous p53 for degradation
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PubMed Central
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20 March 2017
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
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PubMed Central
reference URL
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20 March 2017
The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas
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PubMed Central
reference URL
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20 March 2017
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
retrieved
20 March 2017
Improved survival with MEK inhibition in BRAF-mutated melanoma
1 reference
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PubMed Central
reference URL
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7 April 2017
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
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7 April 2017
Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas
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PubMed Central
reference URL
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29 September 2017
Congenital melanocytic nevi: where are we now? Part I. Clinical presentation, epidemiology, pathogenesis, histology, malignant transformation, and neurocutaneous melanosis.
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PubMed Central
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29 September 2017
Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm
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PubMed Central
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29 September 2017
BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.
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PubMed Central
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29 September 2017
Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm
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PubMed Central
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29 September 2017
Mutant BRAF melanomas--dependence and resistance
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
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29 September 2017
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
1 reference
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PubMed Central
reference URL
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29 September 2017
Development of a highly efficient expression cDNA cloning system: application to oncogene isolation
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PubMed Central
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29 September 2017
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
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2 June 2018
Single substitution within the RKTR motif impairs kinase activity but promotes dimerization of RAF kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
retrieved
2 June 2018
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
retrieved
2 June 2018
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
retrieved
27 November 2018
8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880773
retrieved
27 November 2018
Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24345920
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1078-0432.CCR-13-1746
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4565170
OpenCitations bibliographic resource ID
4565170
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4565170
PMCID
3880773
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4565170
PubMed ID
24345920
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4565170
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