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English
Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib
scientific article
Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
24625776
retrieved
13 November 2016
title
Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib
(English)
1 reference
stated in
PubMed
PubMed ID
24625776
retrieved
13 November 2016
main subject
phase I clinical trial
0 references
patient
1 reference
based on heuristic
inferred from title
author
Eric Lander
series ordinal
18
0 references
Eran Hodis
series ordinal
4
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Jonathan E Rosenberg
object named as
Jonathan E Rosenberg
series ordinal
22
0 references
Leena Gandhi
object named as
Leena Gandhi
series ordinal
9
0 references
Philip W. Kantoff
object named as
Philip W Kantoff
series ordinal
20
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Massimo Loda
series ordinal
15
object named as
Massimo Loda
0 references
Stacey Gabriel
series ordinal
19
object named as
Stacey B Gabriel
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Mary-Ellen Taplin
series ordinal
12
object named as
Mary Ellen Taplin
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Levi A Garraway
series ordinal
21
object named as
Levi A Garraway
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Toni K Choueiri
series ordinal
8
object named as
Toni K Choueiri
0 references
David M. Sabatini
series ordinal
17
object named as
David M Sabatini
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Sabina Signoretti
series ordinal
14
object named as
Sabina Signoretti
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author name string
Nikhil Wagle
series ordinal
1
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Brian C Grabiner
series ordinal
2
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Eliezer M Van Allen
series ordinal
3
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Susanna Jacobus
series ordinal
5
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Jeffrey G Supko
series ordinal
6
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Michelle Stewart
series ordinal
7
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James M Cleary
series ordinal
10
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Aymen A Elfiky
series ordinal
11
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Edward C Stack
series ordinal
13
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Geoffrey I Shapiro
series ordinal
16
0 references
publication date
May 2014
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published in
Cancer Discovery
1 reference
stated in
PubMed
volume
4
0 references
page(s)
546-53
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issue
5
0 references
cites work
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20 March 2017
Genome sequencing identifies a basis for everolimus sensitivity
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
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20 March 2017
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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
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7 April 2017
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial
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PubMed Central
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Genomics-driven oncology: framework for an emerging paradigm
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Safety and feasibility of targeted agent combinations in solid tumours
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Management of treatment-related toxicity with targeted therapies for renal cell carcinoma: evidence-based practice and best practices
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29 September 2017
Activating mutations of TOR (target of rapamycin).
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PubMed Central
reference URL
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29 September 2017
mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome
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29 September 2017
Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors
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29 September 2017
Isolation of hyperactive mutants of mammalian target of rapamycin
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29 September 2017
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
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29 September 2017
Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells
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Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling
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Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122326
retrieved
27 November 2018
Phase I trial of pazopanib in patients with advanced cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122326
retrieved
27 November 2018
Identifiers
DOI
10.1158/2159-8290.CD-13-0353
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3338469
OpenCitations bibliographic resource ID
3338469
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3338469
PMCID
4122326
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3338469
PubMed ID
24625776
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3338469
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