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Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro
scientific article
Effect of MRE11 Loss on PARP-Inhibitor Sensitivity in Endometrial Cancer In Vitro
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scholarly article
1 reference
stated in
PubMed
PubMed ID
24927325
retrieved
13 November 2016
title
Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro
(English)
1 reference
stated in
PubMed
PubMed ID
24927325
retrieved
13 November 2016
main subject
endometrial cancer
1 reference
based on heuristic
inferred from title
author
Aurelia Noske
series ordinal
3
object named as
Aurelia Noske
0 references
Kristian Ikenberg
series ordinal
8
object named as
Kristian Ikenberg
0 references
Holger Moch
series ordinal
9
object named as
Holger Moch
0 references
author name string
Romana Koppensteiner
series ordinal
1
0 references
Eleftherios P Samartzis
series ordinal
2
0 references
Adriana von Teichman
series ordinal
4
0 references
Ioannis Dedes
series ordinal
5
0 references
Myriam Gwerder
series ordinal
6
0 references
Patrick Imesch
series ordinal
7
0 references
Daniel Fink
series ordinal
10
0 references
Manuel Stucki
series ordinal
11
0 references
Konstantin J Dedes
series ordinal
12
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language of work or name
English
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publication date
2014
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published in
PLOS One
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volume
9
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page(s)
e100041
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issue
6
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copyright license
Creative Commons Attribution 4.0 International
start time
13 June 2014
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
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Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells
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Poly (ADP-ribose) polymerase inhibitor LT-626: Sensitivity correlates with MRE11 mutations and synergizes with platinums and irinotecan in colorectal cancer cells
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Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A
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Microsatellite instability induced mutations in DNA repair genes CtIP and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase inhibitors in myeloid malignancies
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MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers
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Searching for synthetic lethality in cancer
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The MRE11 complex: starting from the ends.
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Emerging therapeutic targets in endometrial cancer
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PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
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A monoclonal antibody (MSN-1) against a newly established uterine endometrial cancer cell line (SNG-II) and its application to immunohistochemistry and flow cytometry
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2 June 2018
Effects of cytokines combined with high-dose gamma irradiation on the expression of major histocompatibility complex molecules and intercellular adhesion molecule-1 in human ovarian cancers
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21 January 2018
MRE11 expression is impaired in gastric cancer with microsatellite instability.
1 reference
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reference URL
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21 January 2018
Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer
1 reference
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Crossref
reference URL
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21 January 2018
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27 November 2018
Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24927325
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24927325
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PONE.0100041
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3901779
ADS bibcode
2014PLoSO...9j0041K
0 references
OpenCitations bibliographic resource ID
3901779
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3901779
PMCID
4057395
1 reference
stated in
PubMed
PubMed ID
24927325
retrieved
13 November 2016
PubMed ID
24927325
1 reference
stated in
PubMed
PubMed ID
24927325
retrieved
13 November 2016
ResearchGate publication ID
263099317
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