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Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma
scientific article
Targeting TBK1 Inhibits Migration and Resistance to MEK Inhibitors in Mutant NRAS Melanoma
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scholarly article
1 reference
stated in
PubMed
PubMed ID
24962318
retrieved
13 November 2016
title
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma
(English)
1 reference
stated in
PubMed
PubMed ID
24962318
retrieved
13 November 2016
author name string
Ha Linh Vu
series ordinal
1
0 references
Andrew E Aplin
series ordinal
2
0 references
publication date
October 2014
0 references
published in
Molecular Cancer Research
0 references
volume
12
0 references
page(s)
1509-19
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issue
10
0 references
cites work
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IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2
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Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1
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Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma
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TBK1 regulates prostate cancer dormancy through mTOR inhibition
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SHOC2 and CRAF mediate ERK1/2 reactivation in mutant NRAS-mediated resistance to RAF inhibitor
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Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma
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TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation
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RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival
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29 September 2017
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29 September 2017
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Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK
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27 November 2018
Loss of TBK1 induces epithelial-mesenchymal transition in the breast cancer cells by ERα downregulation.
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27 November 2018
Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1.
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27 November 2018
Melanoma
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Influence of TBK-1 on tumor angiogenesis and microvascular inflammation
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inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1541-7786.MCR-14-0204
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1840103
OpenCitations bibliographic resource ID
1840103
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1840103
PMCID
4482471
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1840103
PubMed ID
24962318
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1840103
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