(Q27853031)

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scientific article (publication date: December 2014)

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scholarly article

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Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study (English)

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acute promyelocytic leukemia

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Martin S. Tallman

19

object named as

Martin S Tallman

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Francesco Lo-Coco

24

object named as

Francesco Lo-Coco

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25

object named as

Bob Löwenberg

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author name string

Antonio R Lucena-Araujo

1

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Haesook T Kim

2

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Rafael H Jacomo

3

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Raul A Melo

4

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Rosane Bittencourt

5

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Ricardo Pasquini

6

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Katia Pagnano

7

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Evandro M Fagundes

8

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Maria de Lourdes Chauffaille

9

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Carlos S Chiattone

10

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Ana Silvia Lima

11

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Guillermo Ruiz-Argüelles

12

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Maria Soledad Undurraga

13

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Lem Martinez

14

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Hau C Kwaan

15

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Robert Gallagher

16

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Charlotte M Niemeyer

17

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Stanley L Schrier

18

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David Grimwade

20

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Arnold Ganser

21

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Nancy Berliner

22

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Raul C Ribeiro

23

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Miguel A Sanz

26

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Eduardo M Rego

27

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publication date

December 2014

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Annals of Hematology

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93

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2001-10

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12

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Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.

1 reference

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21 January 2018

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia

1 reference

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21 January 2018

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

FLT3-activating mutations are associated with poor prognostic features in AML at diagnosis but they are not an independent prognostic factor.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Variable prognostic value of FLT3 internal tandem duplications in patients with de novo AML and a normal karyotype, t(15;17), t(8;21) or inv(16).

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol

1 reference

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21 January 2018

Acute promyelocytic leukemia with t(15;17): frequency of additional clonal chromosome abnormalities and FLT3 mutations.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

FLT-3 aberrations in acute promyelocytic leukaemia: clinicopathological associations and prognostic impact.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Impact of FLT3 internal tandem duplications on Indian acute promyelocytic leukemia patients: prognostic implications.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations in acute promyelocytic leukemia: a systematic review

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: a report from the Children's Oncology Group

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Cytogenetic and morphological findings in 166 patients with de novo acute myeloid leukemia in southern Brazil.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Inference and missing data

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: a multicenter study by the PETHEMA group

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Treatment of acute promyelocytic leukemia with high white cell blood counts

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

FLT3-ITD confers poor prognosis in patients with acute promyelocytic leukemia treated with AIDA protocols: long-term follow-up analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Long FLT3 internal tandem duplications and reduced PML-RARα expression at diagnosis characterize a high-risk subgroup of acute promyelocytic leukemia patients

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Treatment outcome of all-trans retinoic acid/anthracycline combination chemotherapy and the prognostic impact of FLT3/ITD mutation in acute promyelocytic leukemia patients

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Internal tandem duplication and Asp835 mutations of the FMS-like tyrosine kinase 3 (FLT3) gene in acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Clinical relevance of FLT3 gene abnormalities in Brazilian patients with infant leukemia.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Structural and functional alterations of FLT3 in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety, pharmacokinetics, and pharmacodynamics

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657.

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

The cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodies

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

Prognostic implication of FLT3 and Ras gene mutations in patients with acute promyelocytic leukemia (APL): a retrospective study from the European APL Group

1 reference

https://api.crossref.org/works/10.1007%2FS00277-014-2142-9

21 January 2018

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