(Q27853065)

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UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib

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scholarly article

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13 November 2016

UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib (English)

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13 November 2016

colorectal cancer

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inferred from title

colorectal carcinoma

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based on heuristic

inferred from title

5

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1 June 2020

Matthias Dobbelstein

11

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1 June 2020

author name string

H Landmann

1

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1 June 2020

D A Proia

2

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1 June 2020

S He

3

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1 June 2020

L S Ogawa

4

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1 June 2020

T Beißbarth

6

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1 June 2020

M Grade

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1 June 2020

J Gaedcke

8

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1 June 2020

M Ghadimi

9

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1 June 2020

U Moll

10

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1 June 2020

publication date

11 September 2014

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Cell Death and Disease

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1 June 2020

5

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1 June 2020

e1411

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1 June 2020

9

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copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 September 2014

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22 June 2022

https://europepmc.org/article/PMC/4540199

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NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones

1 reference

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1 reference

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UDP-Glucuronosyltransferases

1 reference

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The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer

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Ganetespib and HSP90: translating preclinical hypotheses into clinical promise

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HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer

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UDP-glucuronosyltransferase 1A compromises intracellular accumulation and anti-cancer effect of tanshinone IIA in human colon cancer cells

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1 reference

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10.1038/CDDIS.2014.378

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1 June 2020

2 references

13 November 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25210794%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2 references

13 November 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25210794%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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