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English
Origins and Mechanisms of miRNAs and siRNAs
scientific article (publication date: 20 February 2009)
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scholarly article
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review article
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stated in
Europe PubMed Central
title
Origins and Mechanisms of miRNAs and siRNAs
(English)
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main subject
RNA processing
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1902360
production of small RNA involved in gene silencing by RNA
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070918
small RNA loading onto RISC
2 references
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070923
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070922
heterochromatin assembly by small RNA
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0031048
production of siRNA involved in RNA interference
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070919
author
Erik J. Sontheimer
series ordinal
2
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author name string
Richard W Carthew
series ordinal
1
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language of work or name
English
0 references
publication date
20 February 2009
0 references
published in
Cell
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volume
136
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page(s)
642-55
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issue
4
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cites work
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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
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Purified Argonaute2 and an siRNA form recombinant human RISC
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29 September 2017
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Human let-7a miRNA blocks protein production on actively translating polyribosomes
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29 September 2017
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Characterization of Dicer-deficient murine embryonic stem cells.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
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29 September 2017
Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
RNA polymerase IV directs silencing of endogenous DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
The role of RNA interference in heterochromatic silencing
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
Revealing the world of RNA interference
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
29 September 2017
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
2 June 2018
A hexanucleotide element directs microRNA nuclear import.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
2 June 2018
Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
2 June 2018
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
The birth and death of microRNA genes in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Structural determinants of RNA recognition and cleavage by Dicer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Evidence that microRNAs are associated with translating messenger RNAs in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Tethering RITS to a nascent transcript initiates RNAi- and heterochromatin-dependent gene silencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Plant nuclear RNA polymerase IV mediates siRNA and DNA methylation-dependent heterochromatin formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Specific and potent RNAi in the nucleus of human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Uridine addition after microRNA-directed cleavage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2675692
retrieved
27 November 2018
MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19239886
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELL.2009.01.035
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
608570
OpenCitations bibliographic resource ID
608570
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
608570
PMCID
2675692
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
608570
PubMed ID
19239886
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
608570
ResearchGate publication ID
24037486
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