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Inflammation and metabolic disorders
scientific article (publication date: 14 December 2006)
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instance of
scholarly article
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review article
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stated in
Europe PubMed Central
title
Inflammation and metabolic disorders
(English)
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main subject
inflammation
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author
Gökhan Hotamışlıgil
series ordinal
1
object named as
Gökhan S Hotamisligil
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language of work or name
English
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publication date
14 December 2006
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published in
Nature
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volume
444
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page(s)
860-7
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issue
7121
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cites work
Childhood obesity and a diabetes epidemic
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Insulin resistance and atherosclerosis
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Mediators of Inflammation
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Homology between the mammalian liver and the Drosophila fat body.
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The immune response of Drosophila melanogaster
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Function of GATA transcription factors in preadipocyte-adipocyte transition
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Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes
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TLR4 links innate immunity and fatty acid-induced insulin resistance
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Inflammation and insulin resistance
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Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila
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Impact of obesity on treatment of chronic hepatitis C.
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Inflammation: the link between insulin resistance, obesity and diabetes
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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
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Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
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Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese mice.
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Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
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The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
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The expression of TNF alpha by human muscle. Relationship to insulin resistance
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Influence of TNF-alpha and IL-6 infusions on insulin sensitivity and expression of IL-18 in humans.
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Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.
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Obesity is associated with macrophage accumulation in adipose tissue
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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
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Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
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IKK-beta links inflammation to obesity-induced insulin resistance
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Crossref
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Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
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Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.
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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
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7 January 2021
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Signal transduction by tumor necrosis factor and its relatives
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7 January 2021
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7 January 2021
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7 January 2021
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7 January 2021
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7 January 2021
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Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis
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7 January 2021
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1 reference
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7 January 2021
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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
1 reference
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https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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1 reference
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7 January 2021
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1 reference
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7 January 2021
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1 reference
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Crossref
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7 January 2021
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7 January 2021
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The mammalian unfolded protein response
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Perk is essential for translational regulation and cell survival during the unfolded protein response
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7 January 2021
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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1 reference
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7 January 2021
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inferred from DOI database lookup
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
1 reference
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7 January 2021
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Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
1 reference
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7 January 2021
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1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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inferred from DOI database lookup
The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
based on heuristic
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Involvement of endoplasmic reticulum stress in insulin resistance and diabetes
1 reference
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https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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inferred from DOI database lookup
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
1 reference
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https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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inferred from DOI database lookup
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
1 reference
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reference URL
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7 January 2021
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Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE05485
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7 January 2021
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Reactive oxygen species have a causal role in multiple forms of insulin resistance
1 reference
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7 January 2021
based on heuristic
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction and type 2 diabetes
1 reference
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7 January 2021
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7 January 2021
based on heuristic
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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
1 reference
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7 January 2021
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Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
1 reference
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7 January 2021
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Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases
1 reference
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The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
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7 January 2021
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Peroxisome proliferator-activated receptors: from genes to physiology
1 reference
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Crossref
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7 January 2021
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Functional delivery of a cytosolic tRNA into mutant mitochondria of human cells
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7 January 2021
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Identifiers
DOI
10.1038/NATURE05485
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
98652
Dimensions Publication ID
1042166283
0 references
OpenCitations bibliographic resource ID
98652
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
98652
PubMed ID
17167474
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
98652
ResearchGate publication ID
6633455
0 references
Springer Nature article ID
10.1038/nature05485
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