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English
The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release
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scholarly article
1 reference
stated in
PubMed
PubMed ID
11430818
retrieved
1 December 2016
title
The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release
(English)
1 reference
stated in
PubMed
PubMed ID
11430818
retrieved
1 December 2016
main subject
proteasome-activating activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0036402
Proteasome regulatory particle base subunit RPT2 YDL007W
1 reference
stated in
GOA release 2020-03-11
author name string
A Köhler
series ordinal
1
0 references
P Cascio
series ordinal
2
0 references
D S Leggett
series ordinal
3
0 references
K M Woo
series ordinal
4
0 references
A L Goldberg
series ordinal
5
0 references
D Finley
series ordinal
6
0 references
language of work or name
English
0 references
publication date
June 2001
0 references
published in
Molecular Cell
1 reference
stated in
PubMed
PubMed ID
11430818
retrieved
1 December 2016
volume
7
0 references
page(s)
1143-52
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issue
6
0 references
cites work
Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The proteasome: paradigm of a self-compartmentalizing protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The base of the proteasome regulatory particle exhibits chaperone-like activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The proteasome, a novel protease regulated by multiple mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decelerated degradation of short peptides by the 20S proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human 26 S and 20 S proteasomes generate overlapping but different sets of peptide fragments from a model protein substrate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulatory particle of the Saccharomyces cerevisiae proteasome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for the proteasome regulator PA28alpha in antigen presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of 20S proteasome from yeast at 2.4 A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A gated channel into the proteasome core particle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ubiquitin system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural features of the 26 S proteasome complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opening doors into the proteasome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The proteasome activator 11 S REG (PA28) and class I antigen presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of cell proteins and the generation of MHC class I-presented peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and mechanism of ATP-dependent proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two new proteases in the MHC class I processing pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition of the polyubiquitin proteolytic signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Global unfolding of a substrate protein by the Hsp100 chaperone ClpA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Existence of a molecular ruler in proteasomes suggested by analysis of degradation products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for the activation of 20S proteasomes by 11S regulators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900274-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1097-2765(01)00274-X
0 references
PubMed ID
11430818
1 reference
stated in
PubMed
PubMed ID
11430818
retrieved
1 December 2016
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