(Q27934058)

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rRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit.

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scholarly article

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1 December 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029250%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

rRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit (English)

1 reference

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17 January 2020

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Translation initiation factor eIF5B YAL035W

1 reference

GOA release 2020-03-11

Michael G Acker

3

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17 January 2020

5

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17 January 2020

6

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17 January 2020

author name string

Joo-Ran Kim

2

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17 January 2020

Byung-Sik Shin

1

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17 January 2020

Kathryn N Maher

4

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17 January 2020

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24 November 2008

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17 January 2020

Molecular and Cellular Biology

2 references

1 December 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029250%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

29

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17 January 2020

808-821

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17 January 2020

3

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17 January 2020

describes a project that uses

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11 June 2022

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based on heuristic

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Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Coupled release of eukaryotic translation initiation factors 5B and 1A from 80S ribosomes following subunit joining.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Translation elongation factor 2 anticodon mimicry domain mutants affect fidelity and diphtheria toxin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Specific effects of ribosome-tethered molecular chaperones on programmed -1 ribosomal frameshifting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Termination of translation: interplay of mRNA, rRNAs and release factors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

The joining of ribosomal subunits in eukaryotes requires eIF5B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

X-ray crystal structures of 70S ribosome functional complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

The crystal structure of elongation factor EF-Tu from Thermus aquaticus in the GTP conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

The GTPase superfamily: conserved structure and molecular mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Ribosome structure and the mechanism of translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Initiation factor IF 2 binds to the alpha-sarcin loop and helix 89 of Escherichia coli 23S ribosomal RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

20 March 2017

Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

7 April 2017

G protein mechanisms: insights from structural analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

7 April 2017

Structure of the 30S translation initiation complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Intragenic suppressor mutations restore GTPase and translation functions of a eukaryotic initiation factor 5B switch II mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Global translational responses to oxidative stress impact upon multiple levels of protein synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

The cryo-EM structure of a translation initiation complex from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

An in vivo dual-luciferase assay system for studying translational recoding in the yeast Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Structural studies of eukaryotic elongation factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Complete deletion of yeast chromosomal rDNA repeats and integration of a new rDNA repeat: use of rDNA deletion strains for functional analysis of rDNA promoter elements in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

The G222D mutation in elongation factor Tu inhibits the codon-induced conformational changes leading to GTPase activation on the ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

A complex profile of protein elongation: translating chemical energy into molecular movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Crystal structure of active elongation factor Tu reveals major domain rearrangements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Directed hydroxyl radical probing of 16S rRNA using Fe(II) tethered to ribosomal protein S4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

29 September 2017

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Visualization of release factor 3 on the ribosome during termination of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Ribosomal localization of translation initiation factor IF2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Translational misreading: mutations in translation elongation factor 1alpha differentially affect programmed ribosomal frameshifting and drug sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Specific alterations of the EF-Tu polypeptide chain considered in the light of its three-dimensional structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Effects of the mutation glycine-222----aspartic acid on the functions of elongation factor Tu.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

2 June 2018

Conformational transition of initiation factor 2 from the GTP- to GDP-bound state visualized on the ribosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

27 November 2018

Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

27 November 2018

Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

27 November 2018

Engaging the ribosome: universal IFs of translation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

27 November 2018

Architecture of the protein-conducting channel associated with the translating 80S ribosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

27 November 2018

Visualization of elongation factor Tu on the Escherichia coli ribosome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630678

27 November 2018

Molecular Genetic Structure–Function Analysis of Translation Initiation Factor eIF5B

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for control of protein synthesis in HeLa cells via the elongation rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19029250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00896-08

2 references

1 December 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029250%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029250%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2 references

1 December 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029250%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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