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A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p
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scholarly article
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PubMed
PubMed ID
10611239
retrieved
1 December 2016
title
A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p
(English)
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stated in
PubMed
PubMed ID
10611239
retrieved
1 December 2016
main subject
Exosome nuclease subunit RRP6 YOR001W
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GOA release 2020-03-11
author name string
K T Burkard
series ordinal
1
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J S Butler
series ordinal
2
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language of work or name
English
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publication date
January 2000
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published in
Molecular and Cellular Biology
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stated in
PubMed
PubMed ID
10611239
retrieved
1 December 2016
volume
20
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page(s)
604-16
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issue
2
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cites work
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Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p
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Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation
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Mak21p of Saccharomyces cerevisiae, a homolog of human CAATT-binding protein, is essential for 60 S ribosomal subunit biogenesis
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The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.
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Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation
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The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex
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Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast
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Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively
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A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export
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The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity
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The FIP1 gene encodes a component of a yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase
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The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm
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20 March 2017
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
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Disruption of the gene XRN1, coding for a 5'----3' exoribonuclease, restricts yeast cell growth
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20 March 2017
Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G
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7 April 2017
Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
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7 April 2017
An essential component of the decapping enzyme required for normal rates of mRNA turnover
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A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation
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7 April 2017
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast
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7 April 2017
Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure
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7 April 2017
Premature translational termination triggers mRNA decapping
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7 April 2017
Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript
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PubMed Central
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7 April 2017
The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation
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PubMed Central
reference URL
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7 April 2017
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism
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7 April 2017
The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon
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7 April 2017
RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer
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29 September 2017
Modifications of the 5' cap of mRNAs during Xenopus oocyte maturation: independence from changes in poly(A) length and impact on translation
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29 September 2017
Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis
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29 September 2017
Double-stranded RNA viruses of Saccharomyces cerevisiae.
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29 September 2017
RNA polymerase III defects suppress a conditional-lethal poly(A) polymerase mutation in Saccharomyces cerevisiae.
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29 September 2017
Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3
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29 September 2017
Cytoplasmic 3' poly(A) addition induces 5' cap ribose methylation: implications for translational control of maternal mRNA.
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29 September 2017
Analyzing protein-protein interactions using two-hybrid system
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29 September 2017
Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant
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29 September 2017
Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system
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29 September 2017
Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease
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29 September 2017
Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control
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29 September 2017
A yeast protein that bidirectionally affects nucleocytoplasmic transport.
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29 September 2017
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29 September 2017
Superkiller Mutations in Saccharomyces cerevisiae Suppress Exclusion of M2 Double-Stranded RNA by L-A-HN and Confer Cold Sensitivity in the Presence of M and L-A-HN
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29 September 2017
Structure and function of the nontranscribed spacer regions of yeast rDNA
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29 September 2017
Escherichia coli RNase D. Catalytic properties and substrate specificity
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29 September 2017
Escherichia coli RNase D: sequencing of the rnd structural gene and purification of the overexpressed protein
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PubMed Central
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29 September 2017
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29 September 2017
Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae
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PubMed Central
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29 September 2017
RNA processing in vitro produces mature 3' ends of a variety of Saccharomyces cerevisiae mRNAs
1 reference
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PubMed Central
reference URL
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29 September 2017
Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase
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PubMed Central
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29 September 2017
The exosome: a versatile RNA processing machine.
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2 June 2018
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2 June 2018
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2 June 2018
The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency
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PubMed Central
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2 June 2018
mRNA surveillance mitigates genetic dominance in Caenorhabditis elegans.
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27 November 2018
A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm
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27 November 2018
A common function for mRNA 5' and 3' ends in translation initiation in yeast.
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27 November 2018
Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/10611239
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10611239
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ribosome concentration contributes to discrimination against poly(A)- mRNA during translation initiation in Saccharomyces cerevisiae
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10611239
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Uba2 and Ufd1 proteins of Saccharomyces cerevisiae interact with poly(A) polymerase and affect the polyadenylation activity of cell extracts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10611239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA processing generates the mature 3' end of yeast CYC1 messenger RNA in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10611239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
mRNA surveillance by the Caenorhabditis elegans smg genes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10611239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.20.2.604-616.2000
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Fatcat ID
release_qdpscj52tjezhfcevvsrl5pwoq
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/qdpscj52tjezhfcevvsrl5pwoq
retrieved
24 November 2022
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mapped directly with Wikidata item
PMCID
85144
0 references
PubMed ID
10611239
1 reference
stated in
PubMed
PubMed ID
10611239
retrieved
1 December 2016
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