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RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins
scientific article published on December 15, 1991
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scholarly article
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PubMed
PubMed ID
1763050
retrieved
1 December 2016
title
RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins
(English)
1 reference
stated in
PubMed
PubMed ID
1763050
retrieved
1 December 2016
main subject
Protein farnesyltransferase YDL090C
1 reference
stated in
GOA release 2020-03-11
Bifunctional protein farnesyltransferase/protein geranylgeranyltransferase YKL019W
1 reference
stated in
GOA release 2020-03-11
ras subfamily
1 reference
stated in
Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
alkyl and aryl transferases
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Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
fungal genes
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Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
author
Scott Powers
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6
object named as
S. Powers
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Europe PubMed Central
PubMed ID
1763050
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
author name string
B. He
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1
1 reference
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Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
P. Chen
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
S. Y. Chen
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3
1 reference
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Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
K. L. Vancura
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4
1 reference
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Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
S. Michaelis
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
language of work or name
English
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publication date
15 December 1991
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PubMed
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https://europepmc.org/articles/PMC53137
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Europe PubMed Central
1 reference
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Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
https://europepmc.org/articles/PMC53137?pdf=render
file format
Portable Document Format
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open access
content deliverer
Europe PubMed Central
1 reference
stated in
Europe PubMed Central
PubMed ID
1763050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1763050
retrieved
18 November 2022
https://pnas.org/doi/pdf/10.1073/pnas.88.24.11373
1 reference
stated in
Crossref
DOI
10.1073/PNAS.88.24.11373
reference URL
https://api.crossref.org/works/10.1073/PNAS.88.24.11373
retrieved
18 November 2022
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
1763050
retrieved
1 December 2016
cites work
Genetic analysis of yeast RAS1 and RAS2 genes.
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PubMed Central
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20 March 2017
Differential activation of yeast adenylate cyclase by wild-type and mutant RAS proteins
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20 March 2017
Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases
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20 March 2017
The a-factor pheromone of Saccharomyces cerevisiae is essential for mating
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PubMed Central
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20 March 2017
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
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20 March 2017
Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein
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20 March 2017
Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine
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20 March 2017
The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
Dependence of Ypt1 and Sec4 membrane attachment on Bet2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
Isoprenoid modification of rab proteins terminating in CC or CXC motifs
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
Cloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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20 March 2017
Regulation of the mevalonate pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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7 April 2017
STE16, a new gene required for pheromone production by a cells of Saccharomyces cerevisiae
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Fatty acylation is important but not essential for Saccharomyces cerevisiae RAS function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Role of SGP2, a suppressor of a gpa1 mutation, in the mating-factor signaling pathway of Saccharomyces cerevisiae.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
p21ras is modified by a farnesyl isoprenoid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
retrieved
29 September 2017
Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Prenyl proteins in eukaryotic cells: a new type of membrane anchor
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
A role for isoprenoid lipids in the localization and function of an oncoprotein
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Ras C-terminal processing enzymes--new drug targets?
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PubMed Central
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29 September 2017
Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Membrane-binding domain of the small G protein G25K contains an S-(all-trans-geranylgeranyl)cysteine methyl ester at its carboxyl terminus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Isoprenoid modification and plasma membrane association: critical factors for ras oncogenicity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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29 September 2017
Mammalian and yeast ras gene products: biological function in their heterologous systems
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
A novel yeast mutant defective in the processing of ras proteins: assessment of the effect of the mutation on processing steps
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
Structure and expression of yeast DPR1, a gene essential for the processing and intracellular localization of ras proteins.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
Human lamin B contains a farnesylated cysteine residue
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
Enzymatic coupling of cholesterol intermediates to a mating pheromone precursor and to the ras protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
SRV2, a gene required for RAS activation of adenylate cyclase in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
retrieved
2 June 2018
Yeast CAL1 is a structural and functional homologue to the DPR1 (RAM) gene involved in ras processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
Nonidentical subunits of p21H-ras farnesyltransferase. Peptide binding and farnesyl pyrophosphate carrier functions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
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2 June 2018
Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
retrieved
2 June 2018
RAS2 protein of Saccharomyces cerevisiae undergoes removal of methionine at N terminus and removal of three amino acids at C terminus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53137
retrieved
27 November 2018
Structure of Saccharomyces cerevisiae mating hormone a-factor. Identification of S-farnesyl cysteine as a structural component
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1763050
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1763050
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
rab GTP-binding proteins implicated in vesicular transport are isoprenylated in vitro at cysteines within a novel carboxyl-terminal motif
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1763050
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.88.24.11373
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4086278
ADS bibcode
1991PNAS...8811373H
0 references
OpenCitations bibliographic resource ID
4086278
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4086278
PMCID
53137
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4086278
PubMed ID
1763050
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4086278
ResearchGate publication ID
21392841
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