(Q27937119)

Vam6p YDL077C

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Tethering complex subunit PEP3 YLR148W

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Vps41p YDR080W

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Tethering complex subunit VPS16 YPL045W

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Tethering complex subunit PEP5 YMR231W

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Role of tethering factors in secretory membrane traffic.

author name string

Ruoya Ho

series ordinal

1

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Christopher Stroupe

series ordinal

2

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language of work or name

English

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publication date

October 2016

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1 December 2016

17

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page(s)

1078-90

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issue

10

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cites work

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21 January 2018

Golgi tethering factors

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Membrane trafficking. The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins

21 January 2018

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Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p

21 January 2018

1 reference

A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion

21 January 2018

1 reference

New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion

21 January 2018

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A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole

21 January 2018

1 reference

Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.

21 January 2018

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Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae

21 January 2018

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Human Vam6p promotes lysosome clustering and fusion in vivo

21 January 2018

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The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17

21 January 2018

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Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic

21 January 2018

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Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

21 January 2018

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Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex

21 January 2018

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A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly

21 January 2018

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Identification of the switch in early-to-late endosome transition

21 January 2018

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The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7.

21 January 2018

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RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

21 January 2018

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Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

21 January 2018

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Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b

21 January 2018

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Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

21 January 2018

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Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering.

21 January 2018

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A general amphipathic alpha-helical motif for sensing membrane curvature.

21 January 2018

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The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex

21 January 2018

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Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion.

21 January 2018

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

21 January 2018

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Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes

21 January 2018

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Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

21 January 2018

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Ebola virus entry requires the host-programmed recognition of an intracellular receptor

21 January 2018

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Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism

21 January 2018

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The Candida albicans vacuole is required for differentiation and efficient macrophage killing

21 January 2018

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Candida albicans VPS11 is required for vacuole biogenesis and germ tube formation

21 January 2018

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Role of a VPS41 homologue in starvation response, intracellular survival and virulence of Cryptococcus neoformans

21 January 2018

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Aspergillus nidulans DigA, a potential homolog of Saccharomyces cerevisiae Pep3 (Vps18), is required for nuclear migration, mitochondrial morphology and polarized growth.

21 January 2018

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HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly

21 January 2018

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The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane

21 January 2018

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Vacuole fusion at a ring of vertex docking sites leaves membrane fragments within the organelle

21 January 2018

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Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusion

21 January 2018

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Interdependent assembly of specific regulatory lipids and membrane fusion proteins into the vertex ring domain of docked vacuoles

21 January 2018

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HOPS proofreads the trans-SNARE complex for yeast vacuole fusion

21 January 2018

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Phosphorylation of the effector complex HOPS by the vacuolar kinase Yck3p confers Rab nucleotide specificity for vacuole docking and fusion

21 January 2018

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The major role of the Rab Ypt7p in vacuole fusion is supporting HOPS membrane association

21 January 2018

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Remodeling of organelle-bound actin is required for yeast vacuole fusion

21 January 2018

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Homotypic vacuolar fusion mediated by t- and v-SNAREs.

21 January 2018

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Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

21 January 2018

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A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

21 January 2018

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Docking of yeast vacuoles is catalyzed by the Ras-like GTPase Ypt7p after symmetric priming by Sec18p (NSF)

21 January 2018

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Formation of AP-3 transport intermediates requires Vps41 function

21 January 2018

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The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

21 January 2018

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Vps41 phosphorylation and the Rab Ypt7 control the targeting of the HOPS complex to endosome-vacuole fusion sites

21 January 2018

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Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes

21 January 2018

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Vps41p function in the alkaline phosphatase pathway requires homo-oligomerization and interaction with AP-3 through two distinct domains

21 January 2018

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Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway

21 January 2018

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Asymmetric tethering of flat and curved lipid membranes by a golgin.

21 January 2018

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Mechanisms of membrane curvature sensing

21 January 2018

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Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion

21 January 2018

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A simple method for the preparation of homogeneous phospholipid vesicles

21 January 2018

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