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SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis
scientific article
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Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
10582239
retrieved
1 December 2016
title
SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis
(English)
1 reference
stated in
PubMed
PubMed ID
10582239
retrieved
1 December 2016
main subject
proteolysis
1 reference
based on heuristic
inferred from title
SCF ubiquitin ligase complex subunit HRT3 YLR097C
1 reference
stated in
GOA release 2020-03-11
SCF ubiquitin ligase complex subunit DAS1 YJL149W
1 reference
stated in
GOA release 2020-03-11
Ucc1p YLR224W
1 reference
stated in
GOA release 2020-03-11
Uncharacterized protein YDR131C
1 reference
stated in
GOA release 2020-03-11
SCF ubiquitin ligase complex subunit UFO1 YML088W
1 reference
stated in
GOA release 2020-03-11
phosphorylation
1 reference
based on heuristic
inferred from title
author name string
A R Willems
series ordinal
1
0 references
T Goh
series ordinal
2
0 references
L Taylor
series ordinal
3
0 references
I Chernushevich
series ordinal
4
0 references
A Shevchenko
series ordinal
5
0 references
M Tyers
series ordinal
6
0 references
language of work or name
English
0 references
publication date
29 September 1999
0 references
published in
Philosophical Transactions of the Royal Society B
1 reference
stated in
PubMed
PubMed ID
10582239
retrieved
1 December 2016
volume
354
0 references
page(s)
1533-50
0 references
issue
1389
0 references
cites work
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
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Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway
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The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae
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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
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CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
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The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast
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Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins
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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
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Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats.
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p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase
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Protein modules and signalling networks
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Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha
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SCF and APC: the Yin and Yang of cell cycle regulated proteolysis
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Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A
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20 March 2017
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20 March 2017
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase
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20 March 2017
A genome-wide transcriptional analysis of the mitotic cell cycle
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7 April 2017
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis
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The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation
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7 April 2017
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase
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7 April 2017
Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
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7 April 2017
Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway
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7 April 2017
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry
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7 April 2017
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
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7 April 2017
Silver staining of proteins in polyacrylamide gels
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7 April 2017
Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins
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29 September 2017
sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast
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29 September 2017
Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein
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Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo.
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An additional role for the F-box motif: gene regulation within the Neurospora crassa sulfur control network.
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29 September 2017
Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation
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29 September 2017
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast
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29 September 2017
Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation
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29 September 2017
Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle
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29 September 2017
A LEAFY co-regulator encoded by UNUSUAL FLORAL ORGANS.
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29 September 2017
At the heart of the budding yeast cell cycle
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29 September 2017
Cdk inhibitors in development and cancer
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29 September 2017
Analytical properties of the nanoelectrospray ion source
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29 September 2017
The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start
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29 September 2017
Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
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29 September 2017
p34Cdc28-mediated control of Cln3 cyclin degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
Regulated degradation of the transcription factor Gcn4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
FAR1 and the G1 phase specificity of cell cycle arrest by mating factor in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
Structural comparison of the yeast cell division cycle gene CDC4 and a related pseudogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
Contributions of mass spectrometry to peptide and protein structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
29 September 2017
Proteolysis and the G1-S transition: the SCF connection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
Putting it all together: building a prereplicative complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
Dual role for fimbriata in regulating floral homeotic genes and cell division in Antirrhinum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
Rapid 'de novo' peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
pMPY-ZAP: a reusable polymerase chain reaction-directed gene disruption cassette for Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
2 June 2018
Yeast G1 cyclins are unstable in G1 phase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
27 November 2018
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
27 November 2018
Linkage of replication to start by the Cdk inhibitor Sic1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
retrieved
27 November 2018
Negative regulation of FAR1 at the Start of the yeast cell cycle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
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27 November 2018
Genes that can bypass the CLN requirement for Saccharomyces cerevisiae cell cycle START.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1692661
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27 November 2018
The VHL tumour-suppressor gene paradigm
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10582239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA damage inhibits proteolysis of the B-type cyclin Clb5 in S. cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10582239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Grr1 functions in the ubiquitin pathway in Saccharomyces cerevisiae through association with Skp1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10582239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10582239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10582239
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1098/RSTB.1999.0497
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
696486
OpenCitations bibliographic resource ID
696486
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
696486
PMCID
1692661
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
696486
PubMed ID
10582239
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
696486
ResearchGate publication ID
12719538
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