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Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II.
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scholarly article
1 reference
stated in
PubMed
PubMed ID
10594013
retrieved
1 December 2016
title
Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II.
(English)
1 reference
stated in
PubMed
PubMed ID
10594013
retrieved
1 December 2016
main subject
recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0036031
phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1901921
phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1900018
TFIIH complex serine/threonine-protein kinase subunit KIN28 YDL108W
1 reference
stated in
GOA release 2020-03-11
author name string
C R Rodriguez
series ordinal
1
0 references
E J Cho
series ordinal
2
0 references
M C Keogh
series ordinal
3
0 references
C L Moore
series ordinal
4
0 references
A L Greenleaf
series ordinal
5
0 references
S Buratowski
series ordinal
6
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language of work or name
English
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publication date
January 2000
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published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
10594013
retrieved
1 December 2016
volume
20
0 references
page(s)
104-12
0 references
issue
1
0 references
cites work
Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor
1 reference
stated in
PubMed Central
reference URL
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retrieved
20 March 2017
Activating phosphorylation of the Kin28p subunit of yeast TFIIH by Cak1p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
20 March 2017
Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
20 March 2017
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
20 March 2017
mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor
1 reference
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PubMed Central
reference URL
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20 March 2017
Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I.
1 reference
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PubMed Central
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20 March 2017
Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA.
1 reference
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PubMed Central
reference URL
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20 March 2017
Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
A kinase-cyclin pair in the RNA polymerase II holoenzyme.
1 reference
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PubMed Central
reference URL
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20 March 2017
KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II
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PubMed Central
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20 March 2017
CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
The C-terminal domain of RNA polymerase II couples mRNA processing to transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
20 March 2017
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
Messenger RNA capping enzymes from eukaryotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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20 March 2017
RNA polymerase II is an essential mRNA polyadenylation factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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7 April 2017
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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7 April 2017
Reversible phosphorylation of the C-terminal domain of RNA polymerase II
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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7 April 2017
Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation
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PubMed Central
reference URL
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7 April 2017
Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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7 April 2017
Phosphorylated RNA polymerase II stimulates pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Cak1 is required for Kin28 phosphorylation and activation in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Molecular evolution allows bypass of the requirement for activation loop phosphorylation of the Cdc28 cyclin-dependent kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Dependence of yeast pre-mRNA 3'-end processing on CFT1: a sequence homolog of the mammalian AAUAAA binding factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Partial truncation of the yeast RNA polymerase II carboxyl-terminal domain preferentially reduces expression of glycolytic genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Active site of the mRNA-capping enzyme guanylyltransferase from Saccharomyces cerevisiae: similarity to the nucleotidyl attachment motif of DNA and RNA ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Capping enzyme in eukaryotic mRNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Genetic analysis of the repetitive carboxyl-terminal domain of the largest subunit of mouse RNA polymerase II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
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29 September 2017
The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Conditional mutations occur predominantly in highly conserved residues of RNA polymerase II subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Separation of factors required for cleavage and polyadenylation of yeast pre-mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
29 September 2017
Genetics of transcriptional regulation in yeast: connections to the RNA polymerase II CTD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
2 June 2018
RNA polymerase II C-terminal domain required for enhancer-driven transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
2 June 2018
Identification of phosphorylation sites in the repetitive carboxyl-terminal domain of the mouse RNA polymerase II largest subunit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
2 June 2018
Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85066
retrieved
27 November 2018
RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3'-end processing factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Purification of the Saccharomyces cerevisiae cleavage/polyadenylation factor I. Separation into two components that are required for both cleavage and polyadenylation of mRNA 3' ends
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Growth-related changes in phosphorylation of yeast RNA polymerase II
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
GAL4 Is Regulated by the RNA Polymerase II Holoenzyme–Associated Cyclin-Dependent Protein Kinase SRB10/CDK8
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10594013
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.20.1.104-112.2000
0 references
PMCID
85066
0 references
PubMed ID
10594013
1 reference
stated in
PubMed
PubMed ID
10594013
retrieved
1 December 2016
ResearchGate publication ID
12707372
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