(Q28142896)

Amyloid beta (A4) precursor protein

GOA release 2020-03-11

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GOA release 2020-03-11

Disabled 1

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GOA release 2020-03-11

author name string

R Homayouni

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D S Rice

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M Sheldon

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T Curran

The cells and molecules that make a cerebellum.

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language of work or name

English

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publication date

1 September 1999

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published in

Journal of Neuroscience

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volume

19

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page(s)

7507-15

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issue

17

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cites work

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12 December 2020

Deletion of an endosomal/lysosomal targeting signal promotes the secretion of Alzheimer's disease amyloid precursor protein (APP).

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12 December 2020

Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein li

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12 December 2020

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

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12 December 2020

Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern

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12 December 2020

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

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12 December 2020

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

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12 December 2020

Neuronal position in the developing brain is regulated by mouse disabled-1

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12 December 2020

A phosphotyrosine interaction domain

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12 December 2020

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

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12 December 2020

Scrambler, a new neurological mutation of the mouse with abnormalities of neuronal migration

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12 December 2020

Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

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12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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12 December 2020

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

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12 December 2020

Normal and abnormal biology of the beta-amyloid precursor protein

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12 December 2020

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

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12 December 2020

A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/reelin

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12 December 2020

Two new mutants, ‘trembler’ and ‘reeler’, with neurological actions in the house mouse (Mus musculus L.)

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12 December 2020

Novel domain-specific actions of amyloid precursor protein on developing synapses

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12 December 2020

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

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12 December 2020

Mutant genes in familial Alzheimer's disease and transgenic models

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12 December 2020

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

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12 December 2020

The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion

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12 December 2020

Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration.

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12 December 2020

Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein

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12 December 2020

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.

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12 December 2020

Mode of cell migration to the superficial layers of fetal monkey neocortex

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12 December 2020

Increased gene expression of beta-amyloid precursor protein and its homologues APLP1 and APLP2 in human neuroblastoma cells in response to retinoic acid.

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12 December 2020

A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth

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12 December 2020

Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

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12 December 2020

Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice

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12 December 2020

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites

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12 December 2020

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

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12 December 2020

Distribution of an APP homolog, APLP2, in the mouse olfactory system: a potential role for APLP2 in axogenesis.

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12 December 2020

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage

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12 December 2020

Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.

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12 December 2020

Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody.

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12 December 2020

Amyloid precursor protein is enriched in radial glia: implications for neuronal development.

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12 December 2020

Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo

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12 December 2020

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12 December 2020

The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis

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12 December 2020

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

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12 December 2020

The PTB domain: a new protein module implicated in signal transduction

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12 December 2020

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

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12 December 2020

Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain

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12 December 2020

The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.

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12 December 2020

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

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12 December 2020

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

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12 December 2020

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

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12 December 2020

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

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12 December 2020

Amyloid beta-protein precursor is associated with extracellular matrix

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12 December 2020

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.

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12 December 2020

Physiology and pathology of tau protein kinases in relation to Alzheimer's disease.

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12 December 2020

Reeler: new tales on an old mutant mouse.

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12 December 2020

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

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12 December 2020

OpenCitations bibliographic resource ID

Identifiers

1774310

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