(Q28142998)

English

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

scientific article (publication date: April 2000)

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scholarly article

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8 (English)

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apoptotic process

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Pascal Schneider

object named as

P Schneider

5

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8

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J Tschopp

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author name string

J L Bodmer

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N Holler

2

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S Reynard

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P Vinciguerra

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P Juo

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J Blenis

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language of work or name

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publication date

April 2000

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Nature Cell Biology

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2

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241-3

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Death receptors: signaling and modulation

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Identification and characterization of a new member of the TNF family that induces apoptosis

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https://api.crossref.org/works/10.1038%2F35008667

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The receptor for the cytotoxic ligand TRAIL

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based on heuristic

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An antagonist decoy receptor and a death domain-containing receptor for TRAIL

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https://api.crossref.org/works/10.1038%2F35008667

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Characterization of two receptors for TRAIL

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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

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TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

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TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

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Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

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Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

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TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

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Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1 reference

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based on heuristic

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Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

1 reference

https://api.crossref.org/works/10.1038%2F35008667

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based on heuristic

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Inhibition of death receptor signals by cellular FLIP

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/35008667

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Springer Nature article ID

10.1038/35008667

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