(Q28181052)

1

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Hong Ma

2

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Ella Bossy-Wetzel

3

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Stuart A Lipton

4

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Zhuohua Zhang

5

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Gen-Sheng Feng

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

5 September 2003

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published in

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volume

278

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page(s)

34641-53

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issue

36

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cites work

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The Caenorhabditis elegans EGL-15 signaling pathway implicates a DOS-like multisubstrate adaptor protein in fibroblast growth factor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Gab3, a new DOS/Gab family member, facilitates macrophage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Induced expression and association of the Mona/Gads adapter and Gab3 scaffolding protein during monocyte/macrophage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Essential role for Gab2 in the allergic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Activated ERK2 interacts with and phosphorylates the docking protein GAB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Purification of recombinant Rho/Rac/G25K from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Purification and GTPase-activating protein activity of baculovirus expressed p190.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Determination of GTP loading on Rac and Cdc42 in platelets and fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Dynamic expression of d-CdGAPr, a novel Drosophila melanogaster gene encoding a GTPase activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: essential role of arginine 1695

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Rho GTPases in neuronal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Rho proteins, PI 3-kinases, and monocyte/macrophage motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The role of Notch and Rho GTPase signaling in the control of dendritic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The Sequence of the Human Genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

21 January 2018

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Association between GTPase activators for Rho and Ras families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Nadrin, a novel neuron-specific GTPase-activating protein involved in regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

SYD-1, a presynaptic protein with PDZ, C2 and rhoGAP-like domains, specifies axon identity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Determination of GTP loading on Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200

Modular binding domains in signal transduction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304594200