(Q28187962)

2

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Yuzuru Imai

3

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Ryosuke Takahashi

4

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Bingwei Lu

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

5

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language of work or name

English

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publication date

27 March 2003

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published in

Neuron

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volume

37

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page(s)

911-24

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issue

6

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cites work

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7 January 2021

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

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7 January 2021

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

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7 January 2021

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease.

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7 January 2021

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

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7 January 2021

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

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7 January 2021

A Drosophila model of Parkinson's disease

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7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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7 January 2021

Parkin and the molecular pathways of Parkinson's disease

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7 January 2021

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

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Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

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7 January 2021

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Drosophila embryonic neuroblasts in culture: autonomous differentiation of specific neurotransmitters.

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7 January 2021

Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development.

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7 January 2021

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

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7 January 2021

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

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7 January 2021

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

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7 January 2021

Genetic suppression of polyglutamine toxicity in Drosophila

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7 January 2021

Heritable gene silencing in Drosophila using double-stranded RNA.

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7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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7 January 2021

Parkin is associated with cellular vesicles

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7 January 2021

Genetics of Parkinson's disease and biochemical studies of implicated gene products

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7 January 2021

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

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7 January 2021

The ubiquitin pathway in Parkinson's disease.

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7 January 2021

Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster

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7 January 2021

Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance

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7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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7 January 2021

Neurochemical and neurogenetic correlates of Parkinson's disease.

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7 January 2021

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

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7 January 2021

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

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7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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7 January 2021

Comparative genomics of the eukaryotes

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7 January 2021

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

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7 January 2021

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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7 January 2021

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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7 January 2021

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

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7 January 2021

Alpha-synuclein in Lewy bodies

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7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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7 January 2021

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.

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7 January 2021

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

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7 January 2021

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

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7 January 2021

Differential regulation of choline acetyltransferase expression in adult Drosophila melanogaster brain

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7 January 2021

Oxidative stress and genetics in the pathogenesis of Parkinson's disease

1 reference

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7 January 2021

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900143-0

7 January 2021

Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes.

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7 January 2021