(Q28204432)

English

CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins

scientific article (publication date: August 2003)

CAIR-1/BAG-3 Abrogates Heat Shock Protein-70 Chaperone Complex-mediated Protein Degradation

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scholarly article

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CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins (English)

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CAIR-1/BAG-3 Abrogates Heat Shock Protein-70 Chaperone Complex-mediated Protein Degradation (English)

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DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

molecular chaperones

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protein ubiquitination

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based on heuristic

inferred from title

author name string

Howard Doong

1

1 reference

DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

Kathryn Rizzo

2

1 reference

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

Shengyun Fang

3

1 reference

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

Vyta Kulpa

4

1 reference

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

Allan M Weissman

5

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Elise C Kohn

6

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Allan M. Weissman

5

1 reference

DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

Elise C. Kohn

6

1 reference

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

language of work or name

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publication date

1 August 2003

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14 May 2003

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

number of pages

11

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Journal of Biological Chemistry

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

278

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https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

28490-500

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28490-28500

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DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

31

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DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Modulation of in vivo HSP70 chaperone activity by Hip and Bag-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Bag-1M accelerates nucleotide release for human Hsc70 and Hsp70 and can act concentration-dependent as positive and negative cofactor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Molecular chaperone targeting and regulation by BAG family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Modulation of Akt kinase activity by binding to Hsp90

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Akt signaling: linking membrane events to life and death decisions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Proteasome inhibitors: valuable new tools for cell biologists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Activation of Akt is induced by heat shock and involved in suppression of heat-shock-induced apoptosis of NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Effect of staurosporine on suppression of heat shock gene expression and thermotolerance development in HT-29 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Effect of staurosporine on the transcription of HSP70 heat shock gene in HT-29 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

BAG-1L protein enhances androgen receptor function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Anti-cell death activity promotes pulmonary metastasis of melanoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Scythe: a novel reaper-binding apoptotic regulator.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

BAG-1 accelerates cell motility of human gastric cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209682200

21 January 2018

Identifiers

10.1074/JBC.M209682200

1 reference

DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M209682200

27 March 2017

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