(Q28207224)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signaling (English)

1 reference

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8 November 2019

3

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8 November 2019

author name string

Padma L Channavajhala

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Leeying Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

J Perry Hall

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Wei Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Lih-Ling Lin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Yuhua Zhang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

language of work or name

English

0 references

publication date

15 September 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

8 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

47089-47097

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

8 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

KSR, a novel protein kinase required for RAS signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

KSR stimulates Raf-1 activity in a kinase-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Kinase suppressor of Ras signals through Thr269 of c-Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Kinase suppressor of Ras is ceramide-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

KSR is a scaffold required for activation of the ERK/MAPK module

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

MAP kinase module: the Ksr connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

The Raf/MEK/ERK pathway: new concepts of activation.

21 January 2018

1 reference

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Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Structure and transforming potential of the human cot oncogene encoding a putative protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

KSR modulates signal propagation within the MAPK cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

The protein kinase KSR interacts with 14-3-3 protein and Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

COT kinase proto-oncogene expression in T cells: implication of the JNK/SAPK signal transduction pathway in COT promoter activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

A20 inhibits NF-kappa B activation downstream of multiple Map3 kinases and interacts with the I kappa B signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Cot kinase induces cyclooxygenase-2 expression in T cells through activation of the nuclear factor of activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Chemokines--chemotactic cytokines that mediate inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Mitogen-activated protein kinases and nuclear factor-kappaB regulate Helicobacter pylori-mediated interleukin-8 release from macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expr

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306002200

21 January 2018

Identifiers

DOI

10.1074/JBC.M306002200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12975377%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference