(Q28210330)

2

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L Lamorte

3

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M A Naujokas

4

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H Band

5

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W Y Langdon

6

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M Park

Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity

7

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language of work or name

English

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publication date

November 2001

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published in

Molecular Cell

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volume

8

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page(s)

995-1004

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issue

5

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

1 reference

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7 January 2021

Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

1 reference

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7 January 2021

Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.

1 reference

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7 January 2021

D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.

1 reference

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7 January 2021

The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor

1 reference

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7 January 2021

Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway

1 reference

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7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

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7 January 2021

Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells--regulation by Rho, Rac and Rab small G proteins

1 reference

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7 January 2021

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

1 reference

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7 January 2021

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1 reference

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7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

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7 January 2021

The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor

1 reference

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7 January 2021

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

1 reference

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7 January 2021

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Oncogenic activation of tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Cbl: many adaptations to regulate protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Loss of the exon encoding the juxtamembrane domain is essential for the oncogenic activation of TPR-MET.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Protein tyrosine phosphatase PTP-S binds to the juxtamembrane region of the hepatocyte growth factor receptor Met.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900378-1

7 January 2021