(Q28213265)

Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

21 January 2018

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Mannose 6-phosphate receptors in sorting and transport of lysosomal enzymes

21 January 2018

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Identification of residues essential for carbohydrate recognition by the insulin-like growth factor II/mannose 6-phosphate receptor

21 January 2018

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Recognition of Dictyostelium discoideum lysosomal enzymes is conferred by the amino-terminal carbohydrate binding site of the insulin-like growth factor II/mannose 6-phosphate receptor

21 January 2018

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Localization of the insulin-like growth factor II binding site to amino acids 1508-1566 in repeat 11 of the mannose 6-phosphate/insulin-like growth factor II receptor

21 January 2018

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Characterization of phosphorylation sites in the cytoplasmic domain of the 300 kDa mannose-6-phosphate receptor

21 January 2018

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Cysteine34 of the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor is reversibly palmitoylated and required for normal trafficking and lysosomal enzyme sorting

21 January 2018

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Mechanisms for high affinity mannose 6-phosphate ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor

21 January 2018

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Molecular basis of lysosomal enzyme recognition: three-dimensional structure of the cation-dependent mannose 6-phosphate receptor

21 January 2018

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Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor

21 January 2018

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Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor

21 January 2018

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Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur

21 January 2018

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The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5

21 January 2018

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An insulin-like growth factor II (IGF-II) affinity-enhancing domain localized within extracytoplasmic repeat 13 of the IGF-II/mannose 6-phosphate receptor

21 January 2018

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Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH.

21 January 2018

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Lysosomal hydrolase mannose 6-phosphate uncovering enzyme resides in the trans-Golgi network

21 January 2018

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Differences in the endosomal distributions of the two mannose 6-phosphate receptors

21 January 2018

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Cathepsin D precursors in clathrin-coated organelles from human fibroblasts

21 January 2018

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The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi

21 January 2018

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Re-expression of the mannose 6-phosphate receptors in receptor-deficient fibroblasts. Complementary function of the two mannose 6-phosphate receptors in lysosomal enzyme targeting

21 January 2018

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Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains

21 January 2018

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A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome

21 January 2018

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GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex

21 January 2018

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A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi

21 January 2018

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Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin

21 January 2018

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Sorting of mannose 6-phosphate receptors mediated by the GGAs

21 January 2018

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Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor

21 January 2018

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Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains

21 January 2018

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Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains

21 January 2018

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Structural basis for recognition of acidic-cluster dileucine sequence by GGA1

21 January 2018

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The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

21 January 2018

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Interaction of the cation-dependent mannose 6-phosphate receptor with GGA proteins

21 January 2018

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The GGAs promote ARF-dependent recruitment of clathrin to the TGN

21 January 2018

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Interaction of furin in immature secretory granules from neuroendocrine cells with the AP-1 adaptor complex is modulated by casein kinase II phosphorylation

21 January 2018

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The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals

21 January 2018

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A structural explanation for the recognition of tyrosine-based endocytotic signals

21 January 2018

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A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals

21 January 2018

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Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

21 January 2018

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A selective transport route from Golgi to late endosomes that requires the yeast GGA proteins

21 January 2018

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Yeast Gga coat proteins function with clathrin in Golgi to endosome transport

21 January 2018

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GGAs: roles of the different domains and comparison with AP-1 and clathrin

21 January 2018

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Golgi structure in three dimensions: functional insights from the normal rat kidney cell

21 January 2018

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Organellar relationships in the Golgi region of the pancreatic beta cell line, HIT-T15, visualized by high resolution electron tomography

21 January 2018

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Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network

21 January 2018

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Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif

21 January 2018

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Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cells

21 January 2018

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Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells

21 January 2018

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Mannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGN

21 January 2018

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Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation

21 January 2018

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Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells

21 January 2018

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ATP- and cytosol-dependent release of adaptor proteins from clathrin-coated vesicles: A dual role for Hsc70.

21 January 2018

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A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex

21 January 2018

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Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cells

21 January 2018

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Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

21 January 2018

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Rab7: a key to lysosome biogenesis

21 January 2018

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Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain.

21 January 2018

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Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

21 January 2018

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Syntaxin 6 functions in trans-Golgi network vesicle trafficking

21 January 2018

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Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes

21 January 2018

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Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking

21 January 2018

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Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesicles

21 January 2018

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The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding

21 January 2018

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The Rab5 effector EEA1 interacts directly with syntaxin-6

21 January 2018

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The biogenesis of lysosomes: is it a kiss and run, continuous fusion and fission process?

21 January 2018

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Proper sorting of the cation-dependent mannose 6-phosphate receptor in endosomes depends on a pair of aromatic amino acids in its cytoplasmic tail

21 January 2018

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TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking

21 January 2018

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Recognition of the 300-kDa mannose 6-phosphate receptor cytoplasmic domain by 47-kDa tail-interacting protein

21 January 2018

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Role of Rab9 GTPase in facilitating receptor recruitment by TIP47

21 January 2018

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Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells

21 January 2018

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Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network

21 January 2018

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mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors

21 January 2018

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PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

21 January 2018

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PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic.

21 January 2018

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Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics

21 January 2018

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Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain

21 January 2018

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Identification of three internalization sequences in the cytoplasmic tail of the 46 kDa mannose 6-phosphate receptor

21 January 2018

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Multiple C-terminal motifs of the 46-kDa mannose 6-phosphate receptor tail contribute to efficient binding of medium chains of AP-2 and AP-3.

21 January 2018

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Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.

21 January 2018

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Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene

21 January 2018

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Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality

21 January 2018

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Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells

21 January 2018

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Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK.

21 January 2018

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Insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor mediates paracrine interactions during spermatogonial development

21 January 2018

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Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation

21 January 2018

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The IGF-II receptor system: a G protein-linked mechanism

21 January 2018

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Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

21 January 2018

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Mannose 6-phosphate/insulin-like growth factor II receptor fails to interact with G-proteins. Analysis of mutant cytoplasmic receptor domains

21 January 2018

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Soluble CD26/dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/insulin-like growth factor II receptor

21 January 2018

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Thrombospondin-1 is a major activator of TGF-beta1 in vivo

21 January 2018

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Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor

21 January 2018

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Insulin-like growth factor-II/mannose 6 phosphate receptors facilitate the matrix effects of latent transforming growth factor-beta1 released from genetically modified keratinocytes in a fibroblast/keratinocyte co-culture system

21 January 2018

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Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3).

21 January 2018

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The N terminus of mannose 6-phosphate/insulin-like growth factor 2 receptor in regulation of fibrinolysis and cell migration.

21 January 2018

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Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction

21 January 2018

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The soluble type 2 insulin-like growth factor (IGF-II) receptor reduces organ size by IGF-II-mediated and IGF-II-independent mechanisms.

21 January 2018

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M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

21 January 2018

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Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis

21 January 2018

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Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas

21 January 2018

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M6P/IGF2R is mutated in squamous cell carcinoma of the lung

21 January 2018

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Loss of heterozygosity at the mannose 6-phosphate/insulin-like growth factor 2 receptor locus: a frequent but late event in adrenocortical tumorigenesis

21 January 2018

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Mutation analysis of the gene encoding the human mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in human cell lines resistant to growth inhibition by transforming growth factor beta(1) (TGF-beta(1)).

21 January 2018

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Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations.

21 January 2018

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Molecular architecture and functional model of the endocytic AP2 complex

21 January 2018

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Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

21 January 2018

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Mannose 6-phosphate/insulin-like growth factor 2 receptor, a bona fide tumor suppressor gene or just a promising candidate?

21 January 2018

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Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

21 January 2018

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The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes

21 January 2018

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Proliferin Induces Endothelial Cell Chemotaxis through a G Protein-Coupled, Mitogen-Activated Protein Kinase-Dependent Pathway

21 January 2018

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Protein transport from the secretory to the endocytic pathway in mammalian cells

21 January 2018

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The rate of internalization of the mannose 6-phosphate/insulin-like growth factor II receptor is enhanced by multivalent ligand binding

31 March 2020

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Dimerization of the insulin-like growth factor II/mannose 6-phosphate receptor

31 March 2020

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Systematic mutational analysis of the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor cytoplasmic domain. An acidic cluster containing a key aspartate is important for function in lysosomal enzyme sorting

31 March 2020

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A casein kinase II phosphorylation site in the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor determines the high affinity interaction of the AP-1 Golgi assembly proteins with membranes

31 March 2020

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The 46-kDa mannose 6-phosphate receptor contains multiple binding sites for clathrin adaptors

31 March 2020

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In vivo coupling of insulin-like growth factor II/mannose 6-phosphate receptor to heteromeric G proteins. Distinct roles of cytoplasmic domains and signal sequestration by the receptor

31 March 2020

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Proliferin induces endothelial cell chemotaxis through a G protein-coupled, mitogen-activated protein kinase-dependent pathway

31 March 2020

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M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1

31 March 2020

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Insulin-like growth factor-II/mannose 6-phosphate receptor overexpression reduces growth of choriocarcinoma cells in vitro and in vivo

31 March 2020

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M6P/IGF2R tumor suppressor gene mutated in hepatocellular carcinomas in Japan

31 March 2020

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Stable amino-acid sequence of the Mannose-6-phosphate/insulin-like growth-factor-II receptor in ovarian carcinomas with loss of heterozygosity and in breast-cancer cell lines

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1050

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

494547

1009825202

0 references

494547

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference