(Q28239473)

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CYP3A4 mediates dextropropoxyphene N-demethylation to nordextropropoxyphene: human in vitro and in vivo studies and lack of CYP2D6 involvement

scientific article (publication date: October 2004)

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scholarly article

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CYP3A4 mediates dextropropoxyphene N-demethylation to nordextropropoxyphene: human in vitro and in vivo studies and lack of CYP2D6 involvement (English)

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A A Somogyi

1

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A Menelaou

2

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S V Fullston

3

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language of work or name

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publication date

October 2004

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34

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10

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875-87

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Interaction of propoxyphene with diazepam, alprazolam and lorazepam

1 reference

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Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

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Dextropropoxyphene kinetics after single and repeated oral doses in man.

1 reference

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Association between CYP2C19 genotype and proguanil oxidative polymorphism

1 reference

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Dextropropoxyphene acts as a noncompetitive N-methyl-D-aspartate antagonist

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Pharmacokinetics of dextropropoxyphene and nordextropropoxyphene in young and elderly volunteers after single and multiple dextropropoxyphene dosage

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CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.

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Quinidine: potent inhibition of sparteine and debrisoquine oxidation in vivo.

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Severe acute propoxyphene overdose: plasma concentrations of propoxyphene and norpropoxyphene and the effect of dopamine on circulatory failure

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Propoxyphene hydrochloride. A critical review

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Clinically significant pharmacokinetic drug interactions with carbamazepine. An update

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Dextropropoxyphene overdosage. Pharmacological considerations and clinical management

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10.1080/00498250400008371

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