(Q28240102)

English

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

scientific article (publication date: 13 May 2005)

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scholarly article

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Europe PubMed Central

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9 January 2020

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15772076%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

tuberous sclerosis

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based on heuristic

inferred from title

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based on heuristic

inferred from title

1

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9 January 2020

3

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9 January 2020

Christopher G. Proud

5

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9 January 2020

author name string

Stephen G Finn

2

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9 January 2020

Gareth J Browne

4

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9 January 2020

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publication date

16 March 2005

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9 January 2020

Journal of Biological Chemistry

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9 January 2020

280

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9 January 2020

18717-18727

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9 January 2020

19

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9 January 2020

Regulation of peptide-chain elongation in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Regulation of mammalian translation factors by nutrients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Control of protein synthesis by amino acid availability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Rheb fills a GAP between TSC and TOR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Drug-eluting stents in vascular intervention

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Caspase cleavage of initiation factor 4E-binding protein 1 yields a dominant inhibitor of cap-dependent translation and reveals a novel regulatory motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Management of cellular energy by the AMP-activated protein kinase system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

ATP depletion increases phosphorylation of elongation factor eEF2 in adult cardiomyocytes independently of inhibition of mTOR signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Ischaemia induces changes in the association of the binding protein 4E-BP1 and eukaryotic initiation factor (eIF) 4G to eIF4E in differentiated PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

The multifaceted role of mTOR in cellular stress responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Regulation of TSC2 by 14-3-3 binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

A simple enzymatic fluorimetric method for the determination of triglycerides in 10 microliters of serum.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Autophagic proteolysis: control and specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Mammalian TOR: a homeostatic ATP sensor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414499200

21 January 2018

Identifiers

10.1074/JBC.M414499200

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15772076%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15772076%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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