(Q28240491)

2

0 references

Charles H Drake

3

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Jonathan D Powell

4

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Susan M Hutson

Journal of Biological Chemistry

5

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language of work or name

English

0 references

publication date

4 July 2014

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published in

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volume

289

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issue

27

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page(s)

18793-804

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cites work

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Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

20 March 2017

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Transamination Is Required for α-Ketoisocaproate but Not Leucine to Stimulate Insulin Secretion*

20 March 2017

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20 March 2017

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Immunopharmacology of rapamycin

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Regulation of the branched-chain alpha-ketoacid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease

6 April 2017

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Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle

20 March 2017

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Branched chain aminotransferase isoenzymes. Purification and characterization of the rat brain isoenzyme

20 March 2017

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Branched-chain amino acids and neurotransmitter metabolism: Expression of cytosolic branched-chain aminotransferase (BCATc) in the cerebellum and hippocampus

20 March 2017

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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

6 April 2017

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Bidirectional transport of amino acids regulates mTOR and autophagy

7 April 2017

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Regulation of immune responses by L-arginine metabolism

7 April 2017

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

7 April 2017

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mTOR signaling at a glance

7 April 2017

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A modified model of T-cell differentiation based on mTOR activity and metabolism

7 April 2017

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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.

29 September 2017

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BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

29 September 2017

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Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma

29 September 2017

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Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein e7.

29 September 2017

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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

29 September 2017

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mTOR, metabolism, and the regulation of T-cell differentiation and function

29 September 2017

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Expression of mitochondrial branched-chain aminotransferase and α-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism

29 September 2017

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Effective T-cell recall responses require the taurine transporter Taut

29 September 2017

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Regulation of immune responses by mTOR.

29 September 2017

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29 September 2017

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

29 September 2017

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The metabolic life and times of a T-cell

29 September 2017

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Glutamine addiction: a new therapeutic target in cancer

29 September 2017

1 reference

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Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation

29 September 2017

1 reference

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Metabolism in T cell activation and differentiation

29 September 2017

1 reference

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Anergic T cells are metabolically anergic

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Infectious tolerance via the consumption of essential amino acids and mTOR signaling

29 September 2017

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Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

29 September 2017

1 reference

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Amino acid regulation of TOR complex 1.

29 September 2017

1 reference

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Advances in measuring cellular bioenergetics using extracellular flux

29 September 2017

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Role of arginine metabolism in immunity and immunopathology

29 September 2017

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Amino acids and immune function

29 September 2017

1 reference

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Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Branched-chain [corrected] amino acid metabolism: implications for establishing safe intakes

29 September 2017

1 reference

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Overview of the molecular and biochemical basis of branched-chain amino acid catabolism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Egr-2 and Egr-3 are negative regulators of T cell activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Regulation of T lymphocyte metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Calcium, calcineurin, and the control of transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

A new family of protein kinases--the mitochondrial protein kinases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

ConTra v2: a tool to identify transcription factor binding sites across species, update 2011

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

2 June 2018

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A molecular model of human branched-chain amino acid metabolism

2 June 2018

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Role of mitochondrial transamination in branched chain amino acid metabolism.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Purification of branched chain aminotransferase from rat heart mitochondria

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Transaminase of branched chain amino acids. I. Branched chain amino acids-alpha-ketoglutarate transaminase.

2 June 2018

1 reference

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Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nerves

20 June 2018

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Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR.

21 January 2018

1 reference

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Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats

21 January 2018

1 reference

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Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4

21 January 2018

1 reference

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Quantitative microplate-based respirometry with correction for oxygen diffusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.554113

Slc7a5 helps T cells get with the program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.554113

Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.554113

Revving the engine: signal transduction fuels T cell activation.

21 January 2018

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Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081922

Free and protein-bound amino acids in sow's colostrum and milk

27 November 2018

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12 December 2020

Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes

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12 December 2020

Astrocyte leucine metabolism: significance of branched-chain amino acid transamination

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12 December 2020

mTOR upregulation of glycolytic enzymes promotes tumor development

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12 December 2020

Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release

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12 December 2020

CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction

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12 December 2020