(Q28248971)

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Open access chemical and clinical probes to support drug discovery

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scholarly article

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Open access chemical and clinical probes to support drug discovery (English)

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open-source drug discovery

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inferred from title

1

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object named as

Chas Bountra

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author name string

David J Kerr

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Timothy M Willson

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publication date

July 2009

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Nature Chemical Biology

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5

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436-40

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7

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https://scigraph.springernature.com/pub.10.1038/nchembio0709-436

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Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor

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Algesia and local responses induced by neurokinin A and substance P in human skin and temporal muscle

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12 December 2020

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Chemical genetics: where genetics and pharmacology meet

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Orphan nuclear receptors: shifting endocrinology into reverse

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Rebuilding the R&D engine in big pharma.

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Nuclear receptors and lipid physiology: opening the X-files

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MMPs as therapeutic targets--still a viable option?

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Pain, tenderness, wheal and flare induced by substance-P, bradykinin and 5-hydroxytryptamine in humans

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12 December 2020

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An index to quantify an individual's scientific research output

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https://pubmed.ncbi.nlm.nih.gov/19536100

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Substance P levels in the synovium and synovial fluid from patients with rheumatoid arthritis and osteoarthritis

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Structural genomics and drug discovery: all in the family

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Substance P and arthritis: analysis of plasma and synovial fluid levels.

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Cholesteryl ester transfer protein (CETP) inhibitors: is there life after torcetrapib?

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Genomics versus orphan nuclear receptors--a half-time report

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Development of farnesyl transferase inhibitors: a review

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Small molecules and chemical tools at the interface

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Neuropathic pain: aetiology, symptoms, mechanisms, and management

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Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway

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Large-scale structural biology of the human proteome

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https://pubmed.ncbi.nlm.nih.gov/19536100

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Experimental human muscle pain induced by intramuscular injections of bradykinin, serotonin, and substance P

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https://pubmed.ncbi.nlm.nih.gov/19536100

12 December 2020

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Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase

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Neurotransmitter candidates of somatosensory primary afferent fibres

1 reference

https://pubmed.ncbi.nlm.nih.gov/19536100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NCHEMBIO0709-436

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