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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
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1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
DNA damage
0 references
phosphorylation
0 references
author
Sheau-Yann Shieh
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
M Ikeda
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Y Taya
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
C Prives
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 October 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
91
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
325-334
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
Recruitment of p300/CBP in p53-dependent signal pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA-activated protein kinase from HeLa cell nuclei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of the p53 and mdm-2 Interaction Domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 activates transcription in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic activation of transcription by CBP and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 induction, cell cycle checkpoints, and apoptosis in DNAPK-deficient scid mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the Cryptic Sequence-specific DNA-binding Function of p53 by Protein Kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the specific DNA binding function of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53: puzzle and paradigm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding and modulation of p53 by p300/CBP coactivators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human TAFII31 protein is a transcriptional coactivator of the p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 Phosphorylation: biochemical and functional consequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolysis by calpains: a possible contribution to degradation of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation sites in the amino-terminal region of mouse p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-mdm-2 autoregulatory feedback loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980416-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)80416-X
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
894690
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
OpenCitations bibliographic resource ID
894690
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
894690
PubMed publication ID
9363941
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
894690
stated in
Europe PubMed Central
PubMed publication ID
9363941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9363941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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