(Q28262230)

2

0 references

Susan Bonner-Weir

object named as

Susan Bonner-Weir

6

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Norman Sharpless

object named as

Norman E Sharpless

7

0 references

author name string

Janakiraman Krishnamurthy

1

0 references

Chad Torrice

4

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Angela Koh

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

5

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language of work or name

English

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publication date

28 September 2006

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published in

Nature

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volume

443

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page(s)

453-7

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issue

7110

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Ink4a/Arf expression is a biomarker of aging

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Bmi1, stem cells, and senescence regulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Cancer and ageing: rival demons?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

In vivo proliferation of differentiated pancreatic islet beta cells in transgenic mice expressing mutated cyclin-dependent kinase 4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Genetic evidence for functional dependency of p18Ink4c on Cdk4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Responses of Neonatal Rat Islets to Streptozotocin: Limited B-Cell Regeneration and Hyperglycemia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

The diabetogenic effects of streptozotocin in mice are prolonged and inversely related to age

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN-gamma transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Total body irradiation selectively induces murine hematopoietic stem cell senescence

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Significant Role for p16INK4a in p53-Independent Telomere-Directed Senescence

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

New sources of pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05092

7 January 2021