(Q28263918)

1

0 references

P G McCaffrey

2

0 references

Z Miner

3

0 references

T K Kerppola

4

0 references

J N Lambert

5

0 references

G L Verdine

6

0 references

A Rao

The mechanism of action of cyclosporin A and FK506

8

0 references

language of work or name

English

0 references

publication date

23 September 1993

0 references

published in

Nature

0 references

volume

365

0 references

page(s)

352-5

0 references

issue

6444

0 references

cites work

1 reference

7 January 2021

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

1 reference

7 January 2021

Identification of a putative regulator of early T cell activation genes

1 reference

7 January 2021

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1 reference

7 January 2021

The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer

1 reference

7 January 2021

The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1

1 reference

7 January 2021

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1 reference

7 January 2021

Nuclear factor of activated T cells contains Fos and Jun.

1 reference

7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

7 January 2021

Fos and jun cooperate in transcriptional regulation via heterologous activation domains

1 reference

7 January 2021

Redox regulation of fos and jun DNA-binding activity in vitro

1 reference

7 January 2021

The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB.

1 reference

7 January 2021

Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains

1 reference

7 January 2021

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly

1 reference

7 January 2021

Altered protein conformation on DNA binding by Fos and Jun.

1 reference

7 January 2021

Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativity

1 reference

7 January 2021

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

1 reference

7 January 2021

The basic region of AP-1 specifies glucocorticoid receptor activity at a composite response element

1 reference

7 January 2021

Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro

1 reference

7 January 2021

Functional antagonism between c-Jun and MyoD proteins: a direct physical association

1 reference

7 January 2021

Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression

1 reference

7 January 2021