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A quantitative analysis of kinase inhibitor selectivity
scientific article
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scholarly article
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title
A quantitative analysis of kinase inhibitor selectivity
(English)
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author name string
Mazen W Karaman
series ordinal
1
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Sanna Herrgard
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2
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Daniel K Treiber
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3
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Paul Gallant
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4
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Corey E Atteridge
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5
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Brian T Campbell
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6
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Katrina W Chan
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7
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Pietro Ciceri
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8
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Mindy I Davis
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9
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Philip T Edeen
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10
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Raffaella Faraoni
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11
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Mark Floyd
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12
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Jeremy P Hunt
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13
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Daniel J Lockhart
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14
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Zdravko V Milanov
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15
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Michael J Morrison
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16
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Gabriel Pallares
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17
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Hitesh K Patel
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18
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Stephanie Pritchard
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19
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Lisa M Wodicka
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20
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Patrick P Zarrinkar
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21
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language of work or name
English
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publication date
January 2008
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published in
Nature Biotechnology
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volume
26
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page(s)
127-32
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issue
1
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cites work
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Features of selective kinase inhibitors
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The specificities of protein kinase inhibitors: an update
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A small molecule-kinase interaction map for clinical kinase inhibitors
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The protein kinase complement of the human genome
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Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases
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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
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Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
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MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation
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Molecular basis for specificity in the druggable kinome: sequence-based analysis
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Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
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From oncogene to drug: development of small molecule tyrosine kinase inhibitors as anti-tumor and anti-angiogenic agents
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Kinomics-structural biology and chemogenomics of kinase inhibitors and targets
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Potential benefits of the irreversible pan-erbB inhibitor, CI-1033, in the treatment of breast cancer
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(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta
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CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.
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An efficient rapid system for profiling the cellular activities of molecular libraries.
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High affinity targets of protein kinase inhibitors have similar residues at the positions energetically important for binding
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Gini coefficient: a new way to express selectivity of kinase inhibitors against a family of kinases
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Identifiers
DOI
10.1038/NBT1358
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
549642
Dimensions Publication ID
1029467419
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OpenCitations bibliographic resource ID
549642
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
549642
PubMed ID
18183025
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
549642
ResearchGate publication ID
5667440
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Springer Nature article ID
10.1038/nbt1358
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