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The histone demethylase UTX enables RB-dependent cell fate control
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scholarly article
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title
The histone demethylase UTX enables RB-dependent cell fate control
(English)
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author name string
Jordon K Wang
series ordinal
1
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Miao-Chih Tsai
series ordinal
2
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Gino Poulin
series ordinal
3
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Adam S Adler
series ordinal
4
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Shuzhen Chen
series ordinal
5
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Helen Liu
series ordinal
6
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Yang Shi
series ordinal
7
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Howard Y Chang
series ordinal
8
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language of work or name
English
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publication date
15 February 2010
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published in
Genes & Development
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volume
24
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page(s)
327-32
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issue
4
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cites work
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
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20 March 2017
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
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Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
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The polycomb group protein EZH2 is involved in progression of prostate cancer
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Polycomb silencers control cell fate, development and cancer
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29 September 2017
Cellular mechanisms of tumour suppression by the retinoblastoma gene.
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29 September 2017
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
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29 September 2017
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Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination
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pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.
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29 September 2017
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29 September 2017
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
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29 September 2017
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
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PubMed Central
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2 June 2018
Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816731
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2 June 2018
The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways.
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PubMed Central
reference URL
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2 June 2018
A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling
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PubMed Central
reference URL
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27 November 2018
NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans.
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retrieved
27 November 2018
Identifiers
DOI
10.1101/GAD.1882610
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1574605
Fatcat ID
release_bgevvi2brfb45d2eshe5nhnrj4
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/bgevvi2brfb45d2eshe5nhnrj4
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
1574605
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1574605
PMCID
2816731
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1574605
PubMed ID
20123895
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1574605
ResearchGate publication ID
41399023
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