(Q28275577)

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The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

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The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136 (English)

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1 reference

P Blume-Jensen

1

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R Janknecht

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2

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T Hunter

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3

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language of work or name

English

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publication date

18 June 1998

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published in

Current Biology

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volume

8

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page(s)

779-82

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issue

13

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cites work

The kit ligand encoded at the murine Steel locus: a pleiotropic growth and differentiation factor

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Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

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Lipid-Regulated Kinases: Some Common Themes at Last

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Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C.

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Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells

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Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

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Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm

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Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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(Q28275577)

The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

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