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Emerging mechanisms of eukaryotic DNA replication initiation
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scholarly article
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review article
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Europe PubMed Central
title
Emerging mechanisms of eukaryotic DNA replication initiation
(English)
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author name string
J Leatherwood
series ordinal
1
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language of work or name
English
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publication date
December 1998
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published in
Current Opinion in Cell Biology
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volume
10
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page(s)
742-8
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issue
6
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cites work
Polymerases and the replisome: machines within machines.
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Initiation of DNA replication in eukaryotic cells
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Discrete start sites for DNA synthesis in the yeast ARS1 origin.
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Replication initiation point mapping
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7 January 2021
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ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex
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7 January 2021
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Protein-DNA interactions at a yeast replication origin
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7 January 2021
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Architecture of the yeast origin recognition complex bound to origins of DNA replication
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Conserved initiator proteins in eukaryotes
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7 January 2021
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Isolation of human and fission yeast homologues of the budding yeast origin recognition complex subunit ORC5: human homologue (ORC5L) maps to 7q22.
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Identification of HsORC4, a member of the human origin of replication recognition complex
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7 January 2021
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Interaction between the origin recognition complex and the replication licensing system in Xenopus.
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin
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7 January 2021
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The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast
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7 January 2021
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Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.
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7 January 2021
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A globular complex formation by Nda1 and the other five members of the MCM protein family in fission yeast
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Properties of the nuclear P1 protein, a mammalian homologue of the yeast Mcm3 replication protein
1 reference
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7 January 2021
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MCM proteins: evolution, properties, and role in DNA replication.
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement
1 reference
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Biochemical function of mouse minichromosome maintenance 2 protein
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7 January 2021
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Putting it all together: building a prereplicative complex
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7 January 2021
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Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae
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Cdc7 is required throughout the yeast S phase to activate replication origins.
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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The Cdc7 protein kinase is required for origin firing during S phase
1 reference
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7 January 2021
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Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo.
1 reference
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7 January 2021
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Characterization of an essential Orc2p-associated factor that plays a role in DNA replication
1 reference
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7 January 2021
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Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7
1 reference
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Identification and characterization of a human protein kinase related to budding yeast Cdc7p
1 reference
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7 January 2021
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Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Purification of Hsk1, a minichromosome maintenance protein kinase from fission yeast.
1 reference
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7 January 2021
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Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Cdc2 and Cdc18 with a fission yeast ORC2-like protein
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch?
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role for a Xenopus Orc2-related protein in controlling DNA replication
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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inferred from DOI database lookup
Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the replication initiator protein p65cdc18 by CDK phosphorylation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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inferred from DOI database lookup
Negative regulation of Cdc18 DNA replication protein by Cdc2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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inferred from DOI database lookup
Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle-dependent phosphorylation and dephosphorylation of the yeast DNA polymerase alpha-primase B subunit
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ectopic induction of Clb2 in early G1 phase is sufficient to block prereplicative complex formation in Saccharomyces cerevisiae
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated chromosomal DNA replication in the absence of a nucleus
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
sud1(+) targets cyclin-dependent kinase-phosphorylated Cdc18 and Rum1 proteins for degradation and stops unwanted diploidization in fission yeast
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Geminin, an inhibitor of DNA replication, is degraded during mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC16 controls initiation at chromosome replication origins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Cdc45p, an essential factor required for DNA replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A group of interacting yeast DNA replication genes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of sna41 gene, which is the suppressor of nda4 mutation and is involved in DNA replication in Schizosaccharomyces pombe.
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a gene required for DNA replication in Ustilago maydis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The human homolog of Saccharomyces cerevisiae CDC45
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980117-8
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7 January 2021
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DOI
10.1016/S0955-0674(98)80117-8
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PubMed ID
9914182
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