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The cytochrome P450 4 (CYP4) family
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instance of
scholarly article
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review article
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Europe PubMed Central
title
The cytochrome P450 4 (CYP4) family
(English)
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author name string
A E Simpson
series ordinal
1
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language of work or name
English
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publication date
March 1997
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published in
General Pharmacology
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volume
28
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page(s)
351-9
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issue
3
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cites work
Chlorophenoxyacid herbicides induce microsomal cytochrome P-450 IVA1 (P-452) in rat liver
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
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inferred from DOI database lookup
PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Localization and differential induction of cytochrome P450IVA and acyl-CoA oxidase in rat liver
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential tissue-specific expression and induction of cytochrome P450IVA1 and acyl-CoA oxidase
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in rat primary hepatocyte culture by peroxisome proliferators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatic peroxisome proliferation in rodents and its significance for humans
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lactational transfer of 2,4,5,2',4',5'-hexachlorobiphenyl but not 3,4,3',4'-tetrachlorobiphenyl, induces neonatal CYP4A1
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in rat hepatic drug metabolism during pregnancy and lactation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inducibility and functionality of rat embryonic/foetal cytochrome P-450: A study of differentiating limb-bud and mid-brain cells in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Zonation of cytochrome P450 isozyme expression and induction in rat liver
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential splicing in the 3' non-coding region of rat cytochrome P-452 (P450 IVA1) mRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxisome proliferation and induction of peroxisomal enzymes in mouse and rat liver by dehydroepiandrosterone feeding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cluster of cytochrome P450 genes on the X chromosome of Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of a cytochrome P450 gene of family 4 on the Drosophila X chromosome.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative aspects of the mammalian cytochrome P450 IV gene family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PPAR: a mediator of peroxisome proliferator action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
26 CYP4A subfamily: Functional analysis by immunohistochemistry and in Situ hybridization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and NH2-terminal sequence of cytochrome P-450 from kidney microsomes of untreated male rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction and regulation of cytochrome P450 K-5 (lauric acid hydroxylase) in rat renal microsomes by starvation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and inducibility of cytochrome P450 proteins belonging to families 2,3 and 4 in the rabbit aorta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of preferentially expressed genes in the kidneys of hypertensive rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chlorotrifluoroethylene trimer and tetramer are inducers of the CYP4A subfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and expression of three rabbit kidney cDNAs encoding lauric acid omega-hydroxylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and cDNA cloning of human liver CYP4A fatty acid omega-hydroxylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and NH2-terminal amino acid sequences of human and rat kidney fatty acid omega-hydroxylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA cloning of three new forms of rat brain cytochrome P450 belonging to the CYP4F subfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of two forms of cytochrome P-450 with omega-hydroxylase activities toward prostaglandin A and fatty acids from rabbit liver microsomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of a new form of cytochrome P-450 with prostaglandin A and fatty acid omega-hydroxylase activities from rabbit kidney cortex microsomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renal microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the mechanism of induction of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a rabbit gene encoding a clofibrate-inducible fatty acid omega-hydroxylase: CYP4A6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and properties of pregnancy-inducible rabbit lung cytochrome P-450 prostaglandin omega-hydroxylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The distribution of different forms of cytochrome P-450 in human liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of high-fat diets on hepatic fatty acid oxidation in the rat Isolation of rat liver peroxisomes by vertical-rotor centrifugation by using a self-generated, iso-osmotic, Percoll gradient
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The P450 gene superfamily: recommended nomenclature.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P450 gene nomenclature based on evolution.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental aspects of the hepatic cytochrome P450 monooxygenase system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a new P450 expressed in human lung: complete cDNA sequence, cDNA-directed expression, and chromosome mapping
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth hormone mediates zone-specific gene expression in liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of renal cytochrome P450-dependent arachidonic acid metabolites in hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoelectron microscopic localization of cytochrome P-450 isoenzyme CYP4A1 in liver, ileum and kidney of nafenopin treated male rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of hepatic microsomal CYP4A activity and of peroxisomal beta-oxidation by two non-steroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of rabbit cytochromes P4504A which catalyze the omega-hydroxylation of arachidonic acid, fatty acids, and prostaglandins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of clofibrate-induction of peroxisomal and microsomal fatty acid-oxidizing enzymes by growth hormone and thyroid hormone in primary cultures of rat hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renal cytochrome P450-related arachidonate metabolite inhibits (Na+ + K+)ATPase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome P450-dependent arachidonic acid metabolism in human kidney
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diversity of cytochrome P450 genes in the mosquito, Anopheles albimanus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid β-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translactational induction of CYP4A expression in 10.5-day neonatal rats by the hypolipidemic drug clofibrate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cuticle genes of Drosophila: A developmentally regulated gene cluster
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of cytochrome P450 genes of the CYP4 family in midgut and fat body of the tobacco hornworm, Manduca sexta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of a novel member of the cytochrome P450 subfamily IVA in rat prostate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The immunocytochemical detection of cytochrome P-450 monooxygenase in the lungs of fetal, neonatal, and adult hamsters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of cytochrome P-450 highly active in prostaglandin omega-hydroxylation from lung microsomes of rabbits treated with progesterone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA cloning and expression of the mRNA for cytochrome P-450kd which shows a fatty acid omega-hydroxylating activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of two forms of fatty acid omega-hydroxylase cytochrome P-450 from rabbit kidney cortex microsomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0306-3623%2896%2900246-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0306-3623(96)00246-7
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PubMed ID
9068972
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