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Lysophosphatidic acid: G-protein signalling and cellular responses
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scholarly article
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title
Lysophosphatidic acid: G-protein signalling and cellular responses
(English)
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author name string
W H Moolenaar
series ordinal
1
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O Kranenburg
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2
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F R Postma
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3
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G C Zondag
series ordinal
4
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language of work or name
English
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publication date
April 1997
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published in
Current Opinion in Cell Biology
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volume
9
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page(s)
168-73
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issue
2
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cites work
Lysophosphatidic acid, a multifunctional phospholipid messenger
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7 January 2021
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Lysophosphatidic acid signalling
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Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells
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Lysophosphatidic acid and bFGF control different modes in proliferating myoblasts
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The chemotactic response to PDGF-BB: evidence of a role for Ras.
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Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor
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Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: possible involvement of the mitogen-activated protein kinase cascade.
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Lysophosphatidic acid increases tight junction permeability in cultured brain endothelial cells.
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Xenopus oocytes express multiple receptors for LPA-like lipid mediators.
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Sphingolipid metabolites: members of a new class of lipid second messengers
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Activation of a high affinity Gi protein-coupled plasma membrane receptor by sphingosine-1-phosphate.
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Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
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Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway
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Sphingosylphosphorylcholine activation of mitogen-activated protein kinase in Swiss 3T3 cells requires protein kinase C and a pertussis toxin-sensitive G protein
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Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
1 reference
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Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.
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The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway
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Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.
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Lysophosphatidic acid-induced neurite retraction in PC12 cells: control by phosphoinositide-Ca2+ signaling and Rho
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Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes.
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Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts
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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway
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G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein
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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases
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Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors
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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.
1 reference
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1 reference
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Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway
1 reference
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Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
1 reference
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Crossref
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7 January 2021
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Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma
1 reference
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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors
1 reference
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Crossref
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7 January 2021
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Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins
1 reference
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Crossref
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1 reference
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Crossref
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7 January 2021
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1 reference
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G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly
1 reference
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Crossref
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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
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stated in
Crossref
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7 January 2021
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inferred from DOI database lookup
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
1 reference
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Crossref
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rho-Mediated protein tyrosine phosphorylation in lysophosphatidic-acid-induced tumor-cell invasion
1 reference
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Identifiers
DOI
10.1016/S0955-0674(97)80059-2
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PubMed ID
9069262
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