(Q28323550)

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Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate

scientific article published on November 25, 1990

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Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate (English)

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10.1016/S0021-9258(17)30504-5

https://api.crossref.org/works/10.1016/S0021-9258(17)30504-5

2 November 2022

1 reference

10.1016/S0021-9258(17)30504-5

https://api.crossref.org/works/10.1016/S0021-9258(17)30504-5

2 November 2022

author name string

J. E. Reardon

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1700787

2 November 2022

W. H. Miller

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1700787

2 November 2022

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publication date

25 November 1990

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full work available at URL

http://intl.jbc.org/cgi/content/abstract/265/33/20302

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1700787

2 November 2022

https://api.elsevier.com/content/article/PII:S0021925817305045?httpAccept=text/xml

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10.1016/S0021-9258(17)30504-5

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2 November 2022

https://api.elsevier.com/content/article/PII:S0021925817305045?httpAccept=text/plain

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10.1016/S0021-9258(17)30504-5

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2 November 2022

Journal of Biological Chemistry

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265

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20302-7

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33

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1

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10.1016/S0021-9258(17)30504-5

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Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

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Characterization of the RNA dependent DNA polymerase of a new human T lymphotropic retrovirus (lymphadenopathy associated virus)

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Characterization of the AIDS-associated retrovirus reverse transcriptase and optimal conditions for its detection in virions

4

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3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

5

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10.1016/S0021-9258(17)30504-5

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Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

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3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

8

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2 November 2022

Inhibition of reverse transcriptase activity by 2',3'-dideoxythymidine 5'-triphosphate and its derivatives modified on the 3' position

10

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10.1016/S0021-9258(17)30504-5

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Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5'-triphosphate in comparison to cellular DNA polymerases alpha and beta

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1 reference

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Reverse transcriptases from human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus (SIVMAC) are susceptible to inhibition by foscarnet and 3'-azido-3'-deoxythymidine triphosphate

13

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Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases

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Inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxynucleoside triphosphates: template dependence, and combination with phosphonoformate

15

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10.1016/S0021-9258(17)30504-5

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

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Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

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6 Statistical analysis of enzyme kinetic data

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Thiol reduction of 3'-azidothymidine to 3'-aminothymidine: kinetics and biomedical implications

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Mechanism of HIV reverse transcriptase: enzyme-primer interaction as revealed through studies of a dNTP analogue, 3'-azido-dTTP.

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Kinetic mechanism of DNA polymerase I (Klenow).

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Elementary steps in the DNA polymerase I reaction pathway

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2 November 2022

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