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Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.
scientific article
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stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
title
Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis
(English)
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
main subject
proteolysis
1 reference
based on heuristic
inferred from title
author
John Francis Xavier Diffley
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
Lucy Drury
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
G Perkins
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
language of work or name
English
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publication date
1 September 2001
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Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
The EMBO Journal
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stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
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10 November 2019
volume
20
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
4836-4845
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
17
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation
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29 September 2017
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29 September 2017
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29 September 2017
Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.
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29 September 2017
Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells
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29 September 2017
Sequential function of gene products relative to DNA synthesis in the yeast cell cycle
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29 September 2017
Chromatin-bound Cdc6 persists in S and G2 phases in human cells, while soluble Cdc6 is destroyed in a cyclin A-cdk2 dependent process.
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2 June 2018
F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
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2 June 2018
Cdc18 transcription and proteolysis couple S phase to passage through mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
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2 June 2018
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha.
1 reference
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PubMed Central
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2 June 2018
Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
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2 June 2018
Intracellular location of the Saccharomyces cerevisiae CDC6 gene product.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
retrieved
2 June 2018
Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
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2 June 2018
CDC6 mRNA fluctuates periodically in the yeast cell cycle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
retrieved
2 June 2018
The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
retrieved
27 November 2018
Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
retrieved
27 November 2018
Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
retrieved
27 November 2018
Cdc6p establishes and maintains a state of replication competence during G1 phase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
retrieved
27 November 2018
S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
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27 November 2018
The fission yeast cdc18+ gene product couples S phase to START and mitosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125267
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27 November 2018
CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11532947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11532947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11532947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11532947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11532947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/EMBOJ/20.17.4836
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PMCID
125267
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed ID
11532947
1 reference
stated in
Europe PubMed Central
PMCID
125267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11532947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
ResearchGate publication ID
11813206
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