(Q28365954)

4 July 2017

1 reference

title

The three dimensional structure of the type I insulin-like growth factor receptor (English)

1 reference

4 July 2017

1 reference

C W Ward

1

1 reference

4 July 2017

T P Garrett

2

1 reference

4 July 2017

N M McKern

3

1 reference

4 July 2017

M Lou

4

1 reference

4 July 2017

L J Cosgrove

5

1 reference

4 July 2017

L G Sparrow

6

1 reference

4 July 2017

M J Frenkel

7

1 reference

4 July 2017

P A Hoyne

8

1 reference

4 July 2017

T C Elleman

9

1 reference

4 July 2017

T E Adams

10

1 reference

4 July 2017

G O Lovrecz

11

1 reference

4 July 2017

L J Lawrence

12

1 reference

4 July 2017

P A Tulloch

13

1 reference

4 July 2017

language of work or name

English

0 references

publication date

1 June 2001

1 reference

Journal of Clinical Pathology

4 July 2017

1 reference

4 July 2017

54

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4 July 2017

125-132

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4 July 2017

3

1 reference

Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor

4 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Crystal structure of the tenth type III cell adhesion module of human fibronectin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Crystal structure of the tyrosine kinase domain of the human insulin receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Structure and function of the type 1 insulin-like growth factor receptor.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Disulfide bond structure of human epidermal growth factor receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Identification of the cysteine residues involved in the class I disulfide bonds of the human insulin receptor: properties of insulin receptor monomers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Building proteins with fibronectin type III modules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

The first structure of a receptor tyrosine kinase domain: a further step in understanding the molecular basis of insulin action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Somatomedin receptor of human placenta: solubilization, photolabeling, partial purification, and comparison with insulin receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Primary structure of a putative receptor for a ligand of the insulin family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

A model for the quaternary structure of human placental insulin receptor deduced from electron microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Mutations in insulin-receptor gene in insulin-resistant patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

The ligand specificities of the insulin receptor and the insulin-like growth factor I receptor reside in different regions of a common binding site

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

The NSILA-s receptor in liver plasma membranes. Characterization and comparison with the insulin receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Structural studies of the detergent-solubilized and vesicle-reconstituted insulin receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Mapping of an NH2-terminal ligand binding site of the insulin receptor by alanine scanning mutagenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Unusual insulin binding to cells expressing an insulin receptor mutated at cysteine 524.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Characterization of the insulin and somatomedin-C receptors in human placental cell membranes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Cysteine 647 in the insulin receptor is required for normal covalent interaction between alpha- and beta-subunits and signal transduction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Identification of a disulfide bridge connecting the alpha-subunits of the extracellular domain of the insulin receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Structural organization of the human insulin receptor ectodomain.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Identification of determinants that confer ligand specificity on the insulin receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Insulin-mediated secretion of ecdysteroids from mosquito ovaries and molecular cloning of the insulin receptor homologue from ovaries of bloodfed Aedes aegypti

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1187049

Membrane topology of insulin receptors reconstituted into lipid vesicles

27 November 2018

1 reference

12 December 2020

Chimeric receptors indicate that phenylalanine 39 is a major contributor to insulin specificity of the insulin receptor

1 reference

12 December 2020

Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor

1 reference

12 December 2020

Properties of an insulin receptor with an IGF-1 receptor loop exchange in the cysteine-rich region

1 reference

12 December 2020

Insulin and non-suppressible insulin-like activity (NSILA-s): evidence for separate plasma membrane receptor sites

1 reference

12 December 2020

1 reference

12 December 2020

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor

1 reference

12 December 2020

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

1 reference

12 December 2020

Members of the insulin receptor family contain three fibronectin type III domains

1 reference

12 December 2020

Quaternary structure of the insulin-insulin receptor complex

1 reference

12 December 2020

The disulfide bonds in the C-terminal domains of the human insulin receptor ectodomain

1 reference

12 December 2020

A third fibronectin-type-III domain in the insulin-family receptors

1 reference

12 December 2020

A third fibronectin type III domain in the extracellular region of the insulin receptor family

1 reference

12 December 2020

Single-molecule imaging of human insulin receptor ectodomain and its Fab complexes

1 reference

12 December 2020

Identifiers

DOI

10.1136/MP.54.3.125

1 reference

4 July 2017

1 reference

4 July 2017

1 reference