(Q28505083)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

Ligase IV, DNA, ATP-dependent

5 December 2019

main subject

1 reference

GOA release 2020-03-11

author

Norman Sharpless

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

D O Ferguson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

R C O'Hagan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

D H Castrillon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

C Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

P A Farazi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

S Alson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

J Fleming

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

C C Morton

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

K Frank

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

L Chin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

F W Alt

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

R A DePinho

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

publication date

1 December 2001

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

volume

8

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

page(s)

1187-1196

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

issue

6

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

5 December 2019

cites work

1 reference

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7 January 2021

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7 January 2021

Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma

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7 January 2021

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

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7 January 2021

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

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7 January 2021

The interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis

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7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

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7 January 2021

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

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7 January 2021

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

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7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

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7 January 2021

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

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7 January 2021

Tumour-suppressor genes: evolving definitions in the genomic age

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7 January 2021

Loss of heterozygosity and lack of mutations of the XPG/ERCC5 DNA repair gene at 13q33 in prostate cancer.

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

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7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

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7 January 2021

DNA copy number losses in human neoplasms

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7 January 2021

Identification of recurrent chromosomal rearrangements and the unique relationship between low-level amplification and translocation in glioblastoma.

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7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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7 January 2021

Limitations of chromosome classification by multicolor karyotyping

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7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

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7 January 2021

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

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7 January 2021

The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes

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7 January 2021

Analysis of ku80-mutant mice and cells with deficient levels of p53

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7 January 2021

Multicolour spectral karyotyping of mouse chromosomes

1 reference

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7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

1 reference

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7 January 2021

Cytogenetic analysis in the examination of solid tumors in children

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7 January 2021

The MDM2 gene amplification database

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7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

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7 January 2021

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

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7 January 2021

Characterization of the 12q13-15 amplicon in soft tissue tumors

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7 January 2021

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7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

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7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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7 January 2021

Frequent chromosomal translocations induced by DNA double-strand breaks

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

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7 January 2021

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7 January 2021

Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

3088794

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11779495%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

3088794

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3088794