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Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
title
Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background
(English)
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
main subject
Tuberin
1 reference
stated in
GOA release 2020-03-11
author name string
H. Onda
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
A. Lueck
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
P. W. Marks
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
H. B. Warren
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
D. J. Kwiatkowski
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
language of work or name
English
0 references
publication date
1 September 1999
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
published in
Journal of Clinical Investigation
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
volume
104
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
page(s)
687–695
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
issue
6
1 reference
stated in
PubMed
PubMed ID
10491404
retrieved
24 January 2017
cites work
Comprehensive mutation analysis of TSC1 and TSC2-and phenotypic correlations in 150 families with tuberous sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Comprehensive mutational analysis of the TSC1 gene: observations on frequency of mutation, associated features, and nonpenetrance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Hamartin, the product of the tuberous sclerosis 1 (TSC1) gene, interacts with tuberin and appears to be localized to cytoplasmic vesicles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Identification and characterization of the tuberous sclerosis gene on chromosome 16
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
19 March 2017
Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
The actin-binding proteins adseverin and gelsolin are both highly expressed but differentially localized in kidney and intestine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Renal lesion growth in children with tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Loss of tuberin in both subependymal giant cell astrocytomas and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Subependymal astrocytic hamartomas in the Eker rat model of tuberous sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Allelic loss is frequent in tuberous sclerosis kidney lesions but rare in brain lesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Multifocal renal cell carcinoma in sibs from a chromosome 9 linked (TSC1) tuberous sclerosis family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Subependymal giant cell astrocytoma: a clinical, pathological, and flow cytometric study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
29 September 2017
Widespread loss of gelsolin in breast cancers of humans, mice, and rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
2 June 2018
Gelsolin: a candidate for suppressor of human bladder cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
2 June 2018
Allelic loss at the tuberous sclerosis (Tsc2) gene locus in spontaneous uterine leiomyosarcomas and pituitary adenomas in the Eker rat model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
2 June 2018
Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
2 June 2018
Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
27 November 2018
Malignant tumors of the kidney, brain, and soft tissues in children and young adults with the tuberous sclerosis complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
27 November 2018
Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
27 November 2018
Gelsolin is a downstream effector of rac for fibroblast motility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
27 November 2018
Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408440
retrieved
27 November 2018
Frequent loss of gelsolin expression in non-small cell lung cancers of heavy smokers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10491404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A mutation screen of the TSC1 gene reveals 26 protein truncating mutations and 1 splice site mutation in a panel of 79 tuberous sclerosis patients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10491404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hereditary renal adenomas and adenocarcinomas in rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10491404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10491404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Apparent preferential loss of heterozygosity at TSC2 over TSC1 chromosomal region in tuberous sclerosis hamartomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10491404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI7319
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1331235
OpenCitations bibliographic resource ID
1331235
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1331235
PMCID
408440
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1331235
PubMed ID
10491404
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1331235
ResearchGate publication ID
12809622
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