(Q28507769)

Eukaryotic translation initiation factor 2A

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

5

Douglas R. Cavener

Douglas R

Cavener

1 reference

24 January 2017

6

Craig B

Thompson

Craig B. Thompson

1 reference

24 January 2017

Ekaterina Bobrovnikova-Marjon

1

Ekaterina

Bobrovnikova-Marjon

1 reference

24 January 2017

Georgia Hatzivassiliou

2

Georgia

Hatzivassiliou

1 reference

24 January 2017

Christina Grigoriadou

3

Christina

Grigoriadou

1 reference

24 January 2017

Margarita Romero

4

Margarita

Romero

1 reference

24 January 2017

J. Alan Diehl

7

J Alan

Proceedings of the National Academy of Sciences of the United States of America

Diehl

1 reference

24 January 2017

language of work or name

English

0 references

publication date

21 October 2008

1 reference

24 January 2017

1 reference

24 January 2017

105

1 reference

24 January 2017

16314–16319

1 reference

24 January 2017

42

1 reference

24 January 2017

Regulation of hepatic lipogenesis by the transcription factor XBP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

PERK mediates cell-cycle exit during the mammalian unfolded protein response

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

The mammalian unfolded protein response

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Regulation of sterol synthesis in eukaryotes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis!

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Transcriptional regulation of metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

ATP citrate lyase is an important component of cell growth and transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Mammary physiology and milk secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

The unfolding tale of the unfolded protein response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808517105

PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570995

Use of nile red for the rapid in situ quantitation of lipids on thin-layer chromatograms

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18852460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18852460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18852460