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Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
scientific journal article
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scholarly article
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PubMed
PubMed ID
15578100
retrieved
24 January 2017
title
Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
(English)
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
main subject
apoptotic process
0 references
BCL2-associated X protein
1 reference
stated in
GOA release 2020-03-11
prostaglandin E2
1 reference
based on heuristic
inferred from title
author name string
Teresa G. Tessner
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
Filipe Muhale
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
Terrence E. Riehl
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
Shrikant Anant
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
William F. Stenson
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5
1 reference
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PubMed
PubMed ID
15578100
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24 January 2017
language of work or name
English
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publication date
1 December 2004
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PubMed
PubMed ID
15578100
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24 January 2017
published in
Journal of Clinical Investigation
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stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
volume
114
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stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
page(s)
1676–1685
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stated in
PubMed
PubMed ID
15578100
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24 January 2017
issue
11
1 reference
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PubMed
PubMed ID
15578100
retrieved
24 January 2017
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Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
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The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
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Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.
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27 November 2018
Bax is required for resection-induced changes in apoptosis, proliferation, and members of the extrinsic cell death pathways
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27 November 2018
Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
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27 November 2018
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27 November 2018
Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
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27 November 2018
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529281
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27 November 2018
A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2.
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27 November 2018
Differential sensitivity to apoptosis between the human small and large intestinal mucosae: linkage with segment-specific regulation of BCL-2 homologs and involvement of signaling pathways
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27 November 2018
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.
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27 November 2018
Human intestinal epithelial cell survival: differentiation state-specific control mechanisms
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27 November 2018
Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529281
retrieved
27 November 2018
Disruption of cyclooxygenase-1 gene results in an impaired response to radiation injury.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529281
retrieved
27 November 2018
Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529281
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27 November 2018
Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=529281
retrieved
27 November 2018
Microcolony Survival Assay for Cells of Mouse Intestinal Mucosa Exposed to Radiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15578100
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
16, 16-dimethyl prostaglandin E2 increases survival of murine intestinal stem cells when given before photon radiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15578100
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Colocalization of BAX and BCL-2 in small intestine and kidney biopsies with different degrees of DNA fragmentation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15578100
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Enhancement of tumor response to gamma-radiation by an inhibitor of cyclooxygenase-2 enzyme
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15578100
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15578100
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reduction of spontaneous and irradiation-induced apoptosis in small intestine of IGF-I transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15578100
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI22218
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
Fatcat ID
release_t3d2ydspr5cvxeuxr2pbchveg4
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/t3d2ydspr5cvxeuxr2pbchveg4
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
529281
0 references
PubMed ID
15578100
1 reference
stated in
PubMed
PubMed ID
15578100
retrieved
24 January 2017
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