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Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
title
Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase
(English)
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
main subject
phosphorylation
0 references
Androgen receptor
1 reference
stated in
GOA release 2020-03-11
Thymoma viral proto-oncogene 1
1 reference
stated in
GOA release 2020-03-11
Transformed mouse 3T3 cell double minute 2
1 reference
stated in
GOA release 2020-03-11
ubiquitination
1 reference
based on heuristic
inferred from title
author name string
Hui-Kuan Lin
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
Liang Wang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
Yueh-Chiang Hu
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
Saleh Altuwaijri
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
Chawnshang Chang
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
language of work or name
English
0 references
publication date
1 August 2002
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
published in
The EMBO Journal
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
volume
21
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stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
page(s)
4037–4048
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stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
issue
15
1 reference
stated in
PubMed
PubMed ID
12145204
retrieved
25 January 2017
cites work
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
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PubMed Central
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19 March 2017
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor
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19 March 2017
Mechanisms underlying ubiquitination
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PubMed Central
reference URL
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19 March 2017
Themes and variations on ubiquitylation
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PubMed Central
reference URL
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19 March 2017
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
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reference URL
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19 March 2017
Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells
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19 March 2017
The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex
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19 March 2017
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
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PubMed Central
reference URL
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19 March 2017
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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19 March 2017
From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells
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PubMed Central
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19 March 2017
Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor
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PubMed Central
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19 March 2017
Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate
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PubMed Central
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The ubiquitin system
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Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells
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19 March 2017
Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells
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19 March 2017
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
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PubMed Central
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19 March 2017
Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells
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19 March 2017
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
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19 March 2017
Androgen receptor defects: historical, clinical, and molecular perspectives
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19 March 2017
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
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7 April 2017
Proteasome inhibitors: valuable new tools for cell biologists
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7 April 2017
Androgen receptor (AR) coregulators: an overview
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29 September 2017
Androgen receptor signaling in androgen-refractory prostate cancer
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PubMed Central
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29 September 2017
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth.
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29 September 2017
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway.
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PubMed Central
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29 September 2017
BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway
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PubMed Central
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Inhibiting proteasomes in human HepG2 and LNCaP cells increases endogenous androgen receptor levels
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PubMed Central
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29 September 2017
The RING finger protein SNURF modulates nuclear trafficking of the androgen receptor.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
Proteolysis and the cell cycle: with this RING I do thee destroy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibition
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
RING domains: master builders of molecular scaffolds?
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PubMed Central
reference URL
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29 September 2017
The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
The ubiquitin-proteasome pathway and pathogenesis of human diseases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
Androgen receptor: an overview
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
p53 is mutated in a subset of advanced-stage prostate cancers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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29 September 2017
Receptor protein-tyrosine kinases and their signal transduction pathways
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29 September 2017
Tumour suppressor genes in prostate cancer.
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2 June 2018
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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2 June 2018
p53 represses androgen-induced transactivation of prostate-specific antigen by disrupting hAR amino- to carboxyl-terminal interaction.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=126152
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27 November 2018
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12145204
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12145204
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/EMBOJ/CDF406
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2259569
OpenCitations bibliographic resource ID
2259569
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2259569
PMCID
126152
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2259569
PubMed ID
12145204
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2259569
ResearchGate publication ID
280300449
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