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DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212
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PubMed
PubMed ID
19778506
retrieved
25 January 2017
title
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212
(English)
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PubMed
PubMed ID
19778506
retrieved
25 January 2017
main subject
brain
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Disrupted in schizophrenia 1
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GOA release 2020-03-11
Coiled coil domain containing 88A
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GOA release 2020-03-11
Thymoma viral proto-oncogene 1
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GOA release 2020-03-11
Phosphatase and tensin homolog
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GOA release 2020-03-11
author
Guo-Li Ming
series ordinal
9
object named as
Guo-li Ming
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Hongjun Song
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8
object named as
Hongjun Song
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Eunchai Kang
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7
object named as
Eunchai Kang
1 reference
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PubMed
PubMed ID
19778506
retrieved
25 January 2017
author name string
Ju Young Kim
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1
1 reference
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PubMed
PubMed ID
19778506
retrieved
25 January 2017
Xin Duan
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2
1 reference
stated in
PubMed
PubMed ID
19778506
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25 January 2017
Cindy Y. Liu
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3
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stated in
PubMed
PubMed ID
19778506
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25 January 2017
Mi-Hyeon Jang
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
19778506
retrieved
25 January 2017
Junjie U. Guo
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5
1 reference
stated in
PubMed
PubMed ID
19778506
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25 January 2017
Nattapol Pow-anpongkul
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6
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PubMed
PubMed ID
19778506
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25 January 2017
language of work or name
English
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publication date
24 September 2009
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PubMed
PubMed ID
19778506
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25 January 2017
published in
Neuron
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stated in
PubMed
PubMed ID
19778506
retrieved
25 January 2017
volume
63
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stated in
PubMed
PubMed ID
19778506
retrieved
25 January 2017
page(s)
761–773
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stated in
PubMed
PubMed ID
19778506
retrieved
25 January 2017
issue
6
1 reference
stated in
PubMed
PubMed ID
19778506
retrieved
25 January 2017
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ImageJ
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Europe PubMed Central
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11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3075620/fullTextXML
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The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes
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Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain
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AKT/PKB signaling: navigating downstream
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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3075620
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DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1
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PubMed Central
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Pten regulates neuronal arborization and social interaction in mice
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Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease
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A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
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A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis
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Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles
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Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators
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Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
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Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
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19 March 2017
Neuregulin 1 and susceptibility to schizophrenia
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Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region
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Adult neurogenesis in the mammalian central nervous system
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GABA regulates synaptic integration of newly generated neurons in the adult brain
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Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice
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Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain
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TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment
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29 September 2017
Directed differentiation of hippocampal stem/progenitor cells in the adult brain
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29 September 2017
G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells
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A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition
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29 September 2017
Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.
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29 September 2017
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice
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The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
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29 September 2017
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans
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29 September 2017
Signaling in adult neurogenesis: from stem cell niche to neuronal networks
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Role of DISC1 in neural development and schizophrenia
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29 September 2017
Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways
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29 September 2017
Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia
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29 September 2017
A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions
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29 September 2017
Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function
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29 September 2017
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29 September 2017
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27 November 2018
Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.
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27 November 2018
Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.
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27 November 2018
Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling.
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27 November 2018
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27 November 2018
Seizures accelerate functional integration of adult-generated granule cells.
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27 November 2018
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway.
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27 November 2018
Raf and akt mediate distinct aspects of sensory axon growth
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27 November 2018
Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons
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27 November 2018
Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway
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Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons
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https://pubmed.ncbi.nlm.nih.gov/19778506
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Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19778506
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.NEURON.2009.08.008
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
740014
OpenCitations bibliographic resource ID
740014
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
740014
PMCID
3075620
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
740014
PubMed ID
19778506
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
740014
ResearchGate publication ID
26835522
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