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The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
title
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
(English)
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
main subject
arterial hypertension
1 reference
based on heuristic
inferred from title
phosphorylation
0 references
author
Maria Deak
series ordinal
2
object named as
Maria Deak
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author name string
Alberto C. Vitari
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
Nick A. Morrice
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
Dario R. Alessi
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
language of work or name
English
0 references
publication date
1 October 2005
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
published in
Biochemical Journal
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
volume
391
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
page(s)
17–24
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stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
issue
Pt 1
1 reference
stated in
PubMed
PubMed ID
16083423
retrieved
31 January 2017
cites work
WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
WNK kinases regulate thiazide-sensitive Na-Cl cotransport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Human hypertension caused by mutations in WNK kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Probability-based protein identification by searching sequence databases using mass spectrometry data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
17 March 2017
Regulation of protein kinases; controlling activity through activation segment conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
7 April 2017
Properties of WNK1 and implications for other family members
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
29 September 2017
WNK kinases and the control of blood pressure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
29 September 2017
Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
29 September 2017
Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
29 September 2017
Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
29 September 2017
Three novel missense mutations of WNK4, a kinase mutated in inherited hypertension, in Japanese hypertensives: implication of clinical phenotypes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
29 September 2017
Identification of protein phosphorylation sites by a combination of mass spectrometry and solid phase Edman sequencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
3 June 2018
Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
3 June 2018
The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
3 June 2018
Characterization of a phosphorylation event resulting in upregulation of the salivary Na(+)-K(+)-2Cl(-) cotransporter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1237134
retrieved
27 November 2018
Identifiers
DOI
10.1042/BJ20051180
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4595415
Fatcat ID
release_mcntyxel2vcdfdu2ofnap4speu
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/mcntyxel2vcdfdu2ofnap4speu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
4595415
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4595415
PMCID
1237134
0 references
PubMed ID
16083423
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4595415
ResearchGate publication ID
7677512
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