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Identification of key residues and regions important for porcupine-mediated Wnt acylation
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
title
Identification of key residues and regions important for porcupine-mediated Wnt acylation
(English)
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
main subject
Wingless-type MMTV integration site family, member 3A
1 reference
stated in
GOA release 2020-03-11
Porcupine O-acyltransferase
1 reference
stated in
GOA release 2020-03-11
author name string
Jessica Rios-Esteves
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
Brittany Haugen
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
Marilyn D. Resh
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
language of work or name
English
0 references
publication date
13 June 2014
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
published in
Journal of Biological Chemistry
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
volume
289
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
page(s)
17009–17019
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
issue
24
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
cites work
Structural Studies of Wnts and Identification of an LRP6 Binding Site
1 reference
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PubMed Central
reference URL
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17 March 2017
Wnt/β-catenin signaling and disease
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PubMed Central
reference URL
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17 March 2017
Structural basis of Wnt recognition by Frizzled
1 reference
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PubMed Central
reference URL
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retrieved
17 March 2017
Identification of conserved regions and residues within Hedgehog acyltransferase critical for palmitoylation of Sonic Hedgehog
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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17 March 2017
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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17 March 2017
Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion
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PubMed Central
reference URL
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17 March 2017
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms
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PubMed Central
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17 March 2017
Palmitoylation of intracellular signaling proteins: regulation and function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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17 March 2017
Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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17 March 2017
A role for Wnt signalling in self-renewal of haematopoietic stem cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
17 March 2017
A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
17 March 2017
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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17 March 2017
Identification of a palmitic acid-modified form of human Sonic hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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17 March 2017
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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7 April 2017
Wnt proteins are lipid-modified and can act as stem cell growth factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
7 April 2017
Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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29 September 2017
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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29 September 2017
Protter: interactive protein feature visualization and integration with experimental proteomic data
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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29 September 2017
Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Paracrine Wnt signaling both promotes and inhibits human breast tumor growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Wnt signaling in skin development, homeostasis, and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Identification of N-terminal residues of Sonic Hedgehog important for palmitoylation by Hedgehog acyltransferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Precise regulation of porcupine activity is required for physiological Wnt signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Detecting pore-lining regions in transmembrane protein sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Porcupine-mediated lipidation is required for Wnt recognition by Wls.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Mutation update for the PORCN gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Topological orientation of acyl-CoA:diacylglycerol acyltransferase-1 (DGAT1) and identification of a putative active site histidine and the role of the n terminus in dimer/tetramer formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Transmembrane protein topology prediction using support vector machines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Identification of putative active site residues of ACAT enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Three novel mutations in the PORCN gene underlying focal dermal hypoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Trafficking and signaling by fatty-acylated and prenylated proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
29 September 2017
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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29 September 2017
Dual myristylation and palmitylation of Src family member p59fyn affects subcellular localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
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3 June 2018
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M114.561209
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21 January 2018
The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M114.561209
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21 January 2018
Novel PORCN mutations in focal dermal hypoplasia.
1 reference
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Crossref
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https://api.crossref.org/works/10.1074%2FJBC.M114.561209
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21 January 2018
Lipid-dependent Targeting of G Proteins into Rafts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M114.561209
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21 January 2018
Novel and recurrent PORCN gene mutations in almost unilateral and typical focal dermal hypoplasia patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059143
retrieved
27 November 2018
Iodinated fatty acids as probes for myristate processing and function. Incorporation into pp60v-src
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24798332
retrieved
12 December 2020
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inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M114.561209
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
PMCID
4059143
0 references
PubMed ID
24798332
1 reference
stated in
PubMed
PubMed ID
24798332
retrieved
31 January 2017
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