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PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
title
PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types
(English)
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
main subject
Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
1 reference
stated in
GOA release 2020-03-11
Endothelial PAS domain protein 1
1 reference
stated in
GOA release 2020-03-11
Estrogen related receptor, alpha
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stated in
GOA release 2020-03-11
author
Bruce Spiegelman
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7
object named as
Bruce M. Spiegelman
author given names
Bruce M
author last names
Spiegelman
1 reference
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PubMed
PubMed ID
21106753
retrieved
31 January 2017
Jorge L Ruas
object named as
Jorge L. Ruas
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3
author given names
Jorge L
author last names
Ruas
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PubMed
PubMed ID
21106753
retrieved
21 October 2023
author name string
Kyle A. Rasbach
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1
author given names
Kyle A
author last names
Rasbach
1 reference
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PubMed
PubMed ID
21106753
retrieved
31 January 2017
Rana K. Gupta
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2
author given names
Rana K
author last names
Gupta
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
Jun Wu
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4
author given names
Jun
author last names
Wu
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
Elnaz Naseri
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5
author given names
Elnaz
author last names
Naseri
1 reference
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PubMed
PubMed ID
21106753
retrieved
31 January 2017
Jennifer L. Estall
series ordinal
6
author given names
Jennifer L
author last names
Estall
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
language of work or name
English
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publication date
14 December 2010
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PubMed
PubMed ID
21106753
retrieved
31 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
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stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
volume
107
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
page(s)
21866–21871
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
issue
50
1 reference
stated in
PubMed
PubMed ID
21106753
retrieved
31 January 2017
cites work
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Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin
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Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice
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Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
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Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha
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A conserved family of prolyl-4-hydroxylases that modify HIF
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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
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PubMed Central
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Activation of PPARgamma coactivator-1 through transcription factor docking
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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
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17 March 2017
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
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PubMed Central
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17 March 2017
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres
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PubMed Central
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7 April 2017
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
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7 April 2017
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
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7 April 2017
PGC-1alpha-mediated adaptations in skeletal muscle
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PubMed Central
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29 September 2017
SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.
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29 September 2017
Transcriptional control of preadipocyte determination by Zfp423.
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PubMed Central
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29 September 2017
Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis
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29 September 2017
The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle
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PubMed Central
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29 September 2017
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29 September 2017
NFAT isoforms control activity-dependent muscle fiber type specification
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29 September 2017
Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.
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SirT1 gain of function increases energy efficiency and prevents diabetes in mice
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29 September 2017
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29 September 2017
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29 September 2017
The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha
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29 September 2017
Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer
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29 September 2017
PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.
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PubMed Central
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29 September 2017
PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
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PubMed Central
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29 September 2017
Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.
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29 September 2017
NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching
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29 September 2017
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
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29 September 2017
Hypoxia-inducible factor and its biomedical relevance
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29 September 2017
Calcineurin controls nerve activity-dependent specification of slow skeletal muscle fibers but not muscle growth
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29 September 2017
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.
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29 September 2017
The calcineurin-NFAT pathway and muscle fiber-type gene expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
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29 September 2017
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
1 reference
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PubMed Central
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29 September 2017
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
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29 September 2017
The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene.
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PubMed Central
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29 September 2017
The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells
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29 September 2017
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.
1 reference
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PubMed Central
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29 September 2017
Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo.
1 reference
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PubMed Central
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3 June 2018
Relative workload determines exercise-induced increases in PGC-1alpha mRNA.
1 reference
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27 November 2018
Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
retrieved
27 November 2018
HIF-1alpha in endurance training: suppression of oxidative metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
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27 November 2018
The EPAS1 gene influences the aerobic-anaerobic contribution in elite endurance athletes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
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27 November 2018
A single nucleotide in an estrogen-related receptor alpha site can dictate mode of binding and peroxisome proliferator-activated receptor gamma coactivator 1alpha activation of target promoters.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003089
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27 November 2018
Roles of the calcineurin and CaMK signaling pathways in fast-to-slow fiber type transformation of cultured adult mouse skeletal muscle fibers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21106753
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21106753
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
For a pragmatic approach to exercise studies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21106753
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.1016089107
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2136744
ADS bibcode
2010PNAS..10721866R
0 references
OpenCitations bibliographic resource ID
2136744
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2136744
PMCID
3003089
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2136744
PubMed ID
21106753
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2136744
ResearchGate publication ID
49634984
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