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English
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
9208839
retrieved
31 January 2017
title
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
(English)
1 reference
stated in
PubMed
PubMed ID
9208839
retrieved
31 January 2017
main subject
CD3 antigen, gamma polypeptide
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GOA release 2020-03-11
CD5 antigen
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stated in
GOA release 2020-03-11
CD3 antigen, epsilon polypeptide
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GOA release 2020-03-11
Zeta-chain (TCR) associated protein kinase
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stated in
GOA release 2020-03-11
CD247 antigen
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stated in
GOA release 2020-03-11
Protein tyrosine phosphatase, receptor type, C
1 reference
stated in
GOA release 2020-03-11
CD8 antigen, alpha chain
1 reference
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GOA release 2020-03-11
CD3 antigen, delta polypeptide
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stated in
GOA release 2020-03-11
CD4 antigen
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GOA release 2020-03-11
thymocyte
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author
David L. Wiest
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author name string
D. L. Wiest
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
9208839
retrieved
31 January 2017
J. M. Ashe
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
T. K. Howcroft
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
H. M. Lee
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
D. M. Kemper
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
I. Negishi
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
9208839
retrieved
31 January 2017
D. S. Singer
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
A. Singer
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
R. Abe
series ordinal
9
1 reference
stated in
PubMed
PubMed ID
9208839
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31 January 2017
language of work or name
English
0 references
publication date
1 June 1997
1 reference
stated in
PubMed
PubMed ID
9208839
retrieved
31 January 2017
published in
Immunity
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stated in
PubMed
PubMed ID
9208839
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31 January 2017
volume
6
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stated in
PubMed
PubMed ID
9208839
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31 January 2017
page(s)
663–671
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PubMed
PubMed ID
9208839
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31 January 2017
issue
6
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PubMed
PubMed ID
9208839
retrieved
31 January 2017
cites work
Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein tyrosine kinases in the initiation of antigen receptor signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-Reactivity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the tyrosine kinase domain of the human insulin receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell activation by clustered tyrosine kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of T cell receptor expression and function in immature CD4+CD8+ cells by CD4
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for ZAP-70 in both positive and negative selection of thymocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective events in T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential T cell costimulatory requirements in CD28-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by lymphocyte antigen receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980442-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(00)80442-2
0 references
PubMed ID
9208839
1 reference
stated in
PubMed
PubMed ID
9208839
retrieved
31 January 2017
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