Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28589633)
Watch
English
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
scientific journal article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
title
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
(English)
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
main subject
Werner syndrome RecQ like helicase
1 reference
stated in
GOA release 2020-03-11
Werner syndrome
1 reference
based on heuristic
inferred from title
author name string
M. Lebel
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
P. Leder
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
language of work or name
English
0 references
publication date
27 October 1998
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
volume
95
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
page(s)
13097–13102
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
issue
22
1 reference
stated in
PubMed
PubMed ID
9789047
retrieved
31 January 2017
cites work
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
17 March 2017
Targeted disruption of the mouse topoisomerase I gene by camptothecin selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
17 March 2017
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
17 March 2017
Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
17 March 2017
Mutator phenotype of Werner syndrome is characterized by extensive deletions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
17 March 2017
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
7 April 2017
Positional cloning of the Werner's syndrome gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
7 April 2017
Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Effects of topoisomerase II inhibition in lymphoblasts from patients with progeroid and "chromosome instability" syndromes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
The gene responsible for Werner syndrome may be a cell division "counting" gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
A genetic linkage map of the mouse: current applications and future prospects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Maps from two interspecific backcross DNA panels available as a community genetic mapping resource
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Werner's syndrome: proliferation in vitro of clones of cells bearing chromosome translocations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Werner's syndrome associated with malignancies: five case reports with a survey of case histories in Japan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Escherichia coli RecQ protein is a DNA helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Genetic linkage of Werner's syndrome to five markers on chromosome 8
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Production of homozygous mutant ES cells with a single targeting construct
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
29 September 2017
Cloning of a mouse homologue of the human Werner syndrome gene and assignment to 8A4 by fluorescence in situ hybridization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
A 17S multiprotein form of murine cell DNA polymerase mediates polyomavirus DNA replication in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
Establishment and characterization of testicular cell lines from MT-PVLT-10 transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
Elevated spontaneous mutation rate in SV40-transformed Werner syndrome fibroblast cell lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
Effects of incorporation of 6-thioguanine into SV40 DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
Clonal structural chromosomal rearrangements in lymphocytes of four patients with Werner's syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
Immortalization of Werner syndrome and progeria fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
3 June 2018
Mutagenic consequences of the incorporation of 6-thioguanine into DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
27 November 2018
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
27 November 2018
Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23722
retrieved
27 November 2018
Narrowing the position of the Werner syndrome locus by homozygosity analysis-extension of homozygosity analysis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Fragmentation of centromeric DNA and prevention of homologous chromosome separation in male mouse meiosis in vivo by the topoisomerase II inhibitor etoposide
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA topoisomerases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromosome instability in lymphocytes from a patient with Werner's syndrome is not associated with DNA repair defects
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Homozygosity mapping and Werner's syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9789047
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.95.22.13097
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667311
ADS bibcode
1998PNAS...9513097L
0 references
Fatcat ID
release_n57djwgxtfg7hmvd27xr6rqqlm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/n57djwgxtfg7hmvd27xr6rqqlm
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
667311
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667311
PMCID
23722
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667311
PubMed ID
9789047
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667311
ResearchGate publication ID
13497433
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
